异甘草酸镁治疗慢性乙型肝炎疗效观察

Efficacy of Magnesium Isoglycyrrhizinate in the Treatment of Chronic Hepatitis B

目的观察异甘草酸镁对慢性乙型肝炎的治疗效果。方法 56例慢性乙型肝炎患者随机分为2组,治疗组30例给予异甘草酸镁治疗,对照组26例给予复方甘草酸苷治疗,两组均联合肝水解肽治疗,治疗时间为4周,将两组疗效进行比较。结果两组治疗后在临床症状及肝功能恢复上均明显好转,治疗组有效27例,有效率90%,对照组有效23例,有效率88.5%。异甘草酸镁与复方甘草酸苷治疗效果差异无统计学意义(P>0.05),但在临床症状改善时间及肝功能复常天数上优于复方甘草酸苷(P<0.05)。结论异甘草酸镁治疗慢性乙型肝炎有较好疗效。

Objective To study the effects of Magnesium Isoglycyrrhizinate in the treatment of chronic hepatitis B. Methods A total of 56 patients of chronic hepatitis B patients were randomly divided into treatment group and control group. Treatment group included 30 patients were given Magnesium Isoglycyrrhizinate, and control group included 26 patients were given Glycyrrhizin, the two groups were also given Hydrolysis, compared with the effects of the two groups after treatment 4 weeks. Results There were significant improvement of patients in clinical symptoms and liver function after treatment. The treatment group had 27 cases and 90% efficiency, and the control group had 23 cases and 88.5% efficiency. There was no significant difference on the clinical efficacy between Magnesium Isoglycyrrhizinate and Glycyrrhizin （P 〉 0.05）, but Magnesium Isoglycyrrhizinate could more quickly and effectively relieve clinical symptoms and improve liver function than Glycyrrhizin （P 〈 0.05）. Conclusion Magnesium Isoglycyrrhizinate can be a good choice in the treatment of patients with chronic hepatitis B.