苯磺酸左旋氨氯地平的临床应用进展

Clinical Application Progress of Levamlodipine Besylate

苯磺酸左旋氨氯地平是新一代钙通道阻滞药,由于它去掉了苯磺酸氨氯地平的右旋体,从而大大降低了其不良反应,并因其作用稳定、持久,已广泛应用于临床,成为最常用的降压药物之一。还与其他降压药成为最佳联合用药。它通过降低血压、调节血压昼夜节律、改善血管内皮功能而减少心、脑、肾等重要脏器损害,以降低心脑血管事件的发生率。

Levamlodipine besylate is a new kind of calcium channel blockers.Without the dextrorotatory part,the adverse reaction has declined greatly.The permanence and stabilization of levamlodipine besylate is better than other dihydropyridine calcium channel blockers.At present,levamlodipine besylate has been one of the common drugs in the treatment of hypertention.Furthermore,the combination of levamlodipine besylate and other drugs is also an optimal choice.Levamlodipine besylate can control the blood pressure effectively and placidly,regulate circadian rhythm,and improve vascular endothelial function to decrease the damage to important organs such as heart,brain and kidney to lower the incidence of cardiovascular and cerebrovascular events.