酸枣仁汤加减方治疗失眠的系统评价

Jiajian Suanzaoren Decoction to Treat Insomnia: A Systematic Review

目的:系统评价酸枣仁汤加减方治疗失眠的临床随机对照试验的疗效。方法:检索酸枣仁汤加减方治疗失眠的临床随机对照试验,筛选合格研究,采用Cochrane协作网提供的Rev Man 5.0软件进行Meta-分析。结果:检索到符合纳入标准的临床对照试验文献13篇。Meta-分析结果显示总有效率OR合并=3.12,其95%CI为(2.26,4.30),合并效应量的检验,差异有统计学意义(Z=6.96,P<0.01),可认为酸枣仁汤加减方治疗失眠相对对照组而言有效。漏斗图分析基本对称,敏感性分析显示结果较稳定。结论:酸枣仁汤加减方治疗失眠总有效率优于对照组。

Objective： To evaluate the efficacy of using Jiajian Suanzaoren decoction to treat patients with insomnia.Methods： A comprehensive search strategy was designed to identify all randomized controlled trials（RCTs） comparing Jiajian Suanzaoren decoction with other therapies.A Meta-analysis was performed by Rev Man 5.0 software obtained from the Cochrane Collaboration.Results： Thirteen RCTs met the inclusion criteria.Compared with the control group,the combined outcome of Jiajian Suanzaoren decoction was effective to insomnia[OR 3.12,95% CI（2.26,4.30）,P 0.01].A similar symmetry pattern was seen in the funnel chart and sensitivity analysis was consistent.Conclusion： Jiajian Suanzaoren decoction may have good efficacy to patients with insomnia.