2000～2010年住院COPD患者并发肺栓塞的调查

The investigations of COPD patients with pulmonary embolism hospitalized during 2000～2010

目的了解北京3家医院住院慢性阻塞性肺疾病(COPD)患者并发肺栓塞(PE)的发生率和发病特点,为降低COPD患者合并PE的病死率和防治措施的制定提供科学依据。方法对2000年1月1日至2010年3月20日解放军总医院、北京协和医院及卫生部北京医院的住院病案数据库资料进行回顾性调查。结果按照ICD疾病代码调查住院患者46 700例,其中COPD患者4960例,住院COPD患者并发PE的发生率为0.8%,明显高于非COPD患者0.1%,差异有统计学意义(P<0.001)。COPD患者发生PE的风险明显高于非COPD患者,OR 4.1,95%CI 2.4%～7.1%。不同性别COPD患者并发PE的发生率比较,差异无统计学意义。结论 COPD是导致PE发生和发展的重要危险因素之一,做好COPD的预防和治疗对PE的减少是非常重要的临床路径。

Objective To understand the prevalence and clinical characteristic of pulmonary embolism（PE）in patients with chronic obstructive pulmonary disease（COPD）in Beijing,and to provide clinical information on its prevention and the reduction of its mortality.Methods A retrospectively prevalence survey for in-patient medical database of COPD patients who were discharged from Chinese PLA General Hospital,Peking Union medical college Hospital and Beijing Hospital between January 1st,2000 to March 20th,2010,was carried out.Results According to ICD disease code,46 700 cases were selected,including 4960 COPD patients.The ratio of COPD inpatients with PE was 0.8%,significantly higher than that of non-COPD patients with PE,which was 0.1%,P0.001.Compared with non-COPD patients,COPD patients had significantly higher risk of complicating with pulmonary embolism than non-COPD patients,OR 4.1,95%CI 2.4～7.1%.The difference in prevalence risk of PE between male and female COPD patients was statistically not significant.Conclusions COPD is one of the most important risk factors of PE inducement and development.Therefore,prevention and treatment on COPD have a pivotal role in reducing the occurrence of PE.