社区医院2008～2010年口服降糖药物应用分析

Analysis of oral hypoglycemic drug use in community hospitals:2008～2010

目的分析社区医院口服降糖药的应用特点和发展趋势,为临床合理用药提供参考。方法对宜宾市南岸文化广场社区卫生服务中心2008～2010年口服降糖药应用品种、销售金额、用药频度(DDDS)和日均费用(DDC)进行回顾性分析。结果 3年口服降糖药销售金额占抗糖尿病药总金额80%以上;销售金额、DDDS排序前3位的依次是:双胍类、磺酰脲类、餐时血糖调节剂;3年中,二甲双胍缓释片、格列吡嗪缓释片、瑞格列奈位列单品种销售金额前3位;噻唑烷二酮类DDC最高,二甲双胍缓释片、格列吡嗪缓释片DDC较低,在使用上占主导地位。结论社区口服降糖药用药较合理,双胍类、磺酰脲类、餐时血糖调节剂的应用,与社区医院药物治疗糖尿病策略是相符的。

Objective To analyze retrospectively the status quo and tendency of oral hypoglycemic drug use in community hospitals,and provide basis for rational drug use.Methods The article analyzed statistically oral hypoglycemic drugs used during the period of 2008~2010 in respect of varieties,sales amount,drug daily dosages（DDDS） and defined daily consumption（DDC）.Results The sales amount of oral hypoglycemic drug accounted for more than 80% of the total sales amount of antidiabetic for three successive years.The top three oral hypoglycemic drugs according to sales amount and DDDS were Biguanide,sulfonylurea and prandial glucose regulator.The top three oral hypoglycemic drugs according to sale of single-species were Biguanide,Glipizide Sustained-Release Tablets and Repaglinide.The DDC of thiazolidinediones was the highest,and those of Glipizide Sustained-Release Tablets and Repaglinide were lower,which became the most frequently used drugs in clinic.Conclusion The study shows that the utilization of oral hypoglycemic agents in community hospitals is basically rational.Biguanide,sulfonylurea and prandial glucose regulator are used in the way required by drug therapeutic strategies of diabetes mellitus in community hospital.