肿瘤患者梅毒螺旋体抗体阳性率调查分析

Analysis of The positive rates of anti-treponema pallidum antibody in patients with tumors

目的对住院肿瘤患者的梅毒螺旋体抗体阳性率进行调查分析。方法采用梅毒螺旋体明胶颗粒凝集试验(TP-PA)对确诊为肿瘤的7903例住院患者进行梅毒螺旋体抗体检测,用SPSS11.0软件对梅毒螺旋体抗体阳性率进行统计学分析。结果肿瘤患者梅毒螺旋体抗体阳性率为3.12%;男、女性肿瘤患者梅毒螺旋体抗体阳性率分别为3.18%、3.07%,差异无统计学意义(P>0.05);女性生殖道肿瘤(主要为宫颈癌)患者梅毒螺旋体抗体检测阳性率高于其他肿瘤患者,差异有统计学意义(P<0.05)。结论肿瘤患者梅毒螺旋体抗体阳性率较一般人群高;女性生殖道肿瘤(主要为宫颈癌)患者可能为梅毒螺旋体易感人群。

Objective To investigate and analyze anti-treponema pallidum antibody（anti-TP） in patients with tumors.Methods Treponema pallidum particle agglutination assay（TPPA）was performed to detect anti-TP in 7 903 cases of definitely diagnosed patient with tumor. SPSS11.0 software was applied to statistically analyze positive rate of anti-TP.Results The positive rates of anti-TP were 3.12% in patients with tumors,3.18% in male patients,and 3.07% in female patients,between which there was no statistical difference（P0.05）. The positive rate of anti-TP in patients with feminine genital tract neoplasm,the majority of which was cervical cancer,was significantly higher than that in patients with other tumors（P0.05）.Conclusion The positive rate of anti-TP in patients with tumors might be higher than normal crowd. Patients with feminine genital tract neoplasm,the majority of which was cervical cancer,could be more susceptible for treponema pallidum infection.