复方益肺督气胶囊对慢性阻塞性肺疾病稳定期的疗效及血清白介素-8的影响

Curative effects of compund Yifei Duqi capsules on stable chronic obstructive pulmonary disease and effect of it on serum interleukin-8

目的观察复方益肺督气胶囊治疗慢性阻塞性肺疾病(COPD)稳定期患者临床疗效及对血清IL-8的影响。方法将COPD稳定期患者60例,随机分为对照组、治疗组各30例,对照组吸入噻托溴铵,治疗组口服复方益肺督气胶囊,观察治疗前和治疗3个月后的各项指数。结果治疗3个月后,治疗组血清IL-8明显下降,临床症状较治疗前有明显改善,临床疗效显著优于对照组(P<0.05)。结论复方益肺督气胶囊对COPD稳定期患者血清IL-8有明显抑制作用;改善COPD患者的生活质量。与噻托溴铵相比,不良反应发生率更低,患者依从性良好,经济负担更轻。

Objective To observe curative effects of compund Yifei Duqi capsules on chronic obstructive pulmonary disease（COPD） in stabilization and effect of it on serum interleukin-8.Methods 60 patients with COPD were divided randomly into control and treatment groups,30 patients in each group.The patients in control group were treated with tiotropium bromide and in treatment group with compund Yifei Duqi capsules,and then,all the indexes were measured after 3 months treatmentr.Results the serum IL-8 in treatment group was obviously lowered,the curative effects were improved significantly than that in control group（P〈0.05）.Conclusion Compund Yifei Duqi capsules is significant to inhibit serum IL-8 levels in the stationary COPD and improve the life quality of the patients,and the adverse reaction of the capsules is lower than that of tiotropium bromide.