围产期胎儿炎症反应综合征发生及防治的研究进展

Progress in occurrence and prevention of perinatal fetal inflammatory response syndrome

胎儿炎症反应综合征可能与各种围产儿不良结局密切相关,其病因、发病机制及防治方法尚存在争议.除感染外,宫内慢性缺氧也是诱发其发生的重要因素,多种细胞因子参与的免疫反应在其发生中起重要作用,抗生素辅助免疫调节剂联合皮质类固醇激素是防治其发生的有效手段.

Fetal inflammatory response syndrome （FIRS） maybe closely associated with a variety of adverse perinatal outcomes, but its etiology, pathogenesis and prevention methods are still controversial. In addition to infection, fetal chronic hypoxia also is an important factor inducing its occurrence, and immune response involving many cytokines plays an important role in its occurrence. Treatment of antibiotics combined with immunomodulating agent and corticosteroids is an effective means of preventive treatment.