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巨噬细胞与胰岛素抵抗研究进展 被引量:1

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摘要 肥胖是胰岛素抵抗(IR)的主要原因,是2型糖尿病进展的重要风险因素,是一种低度炎性反应状态。有研究发现,在某些肥胖个体脂肪组织巨噬细胞占40%。巨噬细胞通过表达和分泌促炎因子在IR方面发挥了重要的作用。本文重点探讨巨噬细胞、炎症和IR之间联系,及巨噬细胞对胰岛素介导的炎症起始反应的分子机制和对胰岛素靶组织的影响。
出处 《实用医学杂志》 CAS 北大核心 2011年第20期3796-3798,共3页 The Journal of Practical Medicine
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参考文献23

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