3Liu H, Li W, Wang X, et al. Early gut mucosal dysfunction in patients with acute pancreatitis [J]. Pancreas, 2008,36(2): 192-196.
4Chiu C J, McArdle A H, Brown R, etal. Intestinal mucosal lesion in low-flow states. A morphologic hemodynamic and metabolic reappraisal [J]. Arch Surg, 1970,101 (4) :478-483.
5Rahman S H, Ammori B J, Holmfield J, et al. Intestinal hypoperfusion contributes to gut barrier failure in severe acute pancreatitis [ J ]. Gastroinet Sugr, 2003,7 ( 1 ) : 26-35.
6Bhatia M, Brady M, Shokuhi S, et al. Inflammatory mediators in acute pancreatitis [J]. J Pathol, 2000,190(2):117-125.
7Ma T Y, Boivin M A, Ye D, et al. Mechanism of TNF-alpha modulation of Caco-2 intestinal epithelial tight junction harrier: role of myosin light-chain kinase protein expression [J]. Am J Physio Gastrointest Liver Physiol, 2005,288(3): G422-430.
8Li Q, Zhang Q, Wang M, et al lnterferon-γand tumor necrosis factor-α disrupt epithelial barrier function by altering lipid composition inmembrane microdomains of tight junction [J ]. Clin Immunol, 2008,126( 1 ) :67-80.
9Lewis K, Caldwell J, Phan V, et al. Decreased epithelial barrier function evoked by exposure tometabolic stress and nonpathogenice, coli is enhanced by TNF-alpha [J]. Am J Phvsiol Gastrointest Liver Physiol, 2008. 294(3) : G66-69.
10Xavier R J, Podolsky D K. Unravelling in the pathogenesis of flammatory bowel disease [J]. Nature, 2007,448 (7152) :42- 47.
