支气管肺泡灌洗及注药治疗难治性肺炎32例疗效观察

Bronchoalveolar Lavage and Drug Injection by Bronchofibroscope in 32 Patients with Refractory Pneumonia

目的:探讨经纤支镜支气管肺泡灌洗并注药治疗难治性肺炎的疗效和安全性。方法:将52例难治性肺炎患者分为治疗组和对照组,治疗组32例,对照组20例;两组均以常规抗感染、祛痰、吸氧,治疗组在此基础上予纤支镜行支气管肺泡灌洗、局部给药;比较两组的治疗效果。结果:对照组有效11例,有效率为55%;治疗组有效26例,有效率为87.5%;治疗组的疗效明显高于对照组(P<0.05)。治疗组的住院天数,出院费用均低于对照组(P<0.01)。结论:经纤支镜支气管肺泡灌洗并注药治疗难治性肺炎安全有效,能减少患者住院天数,减低住院费用,值得临床推广。

Objective： To study the efficacy and safety of bronchoalveolar lavage and drug injection by bronchofibroscope in patients with refractory pneumonia. Method： 52 cases with refractory pneumonia were divided into therapy group（32 cases） and control group（20 cases）.All patients were treated with conventional anti-infection,eliminating phlegm,oxygen therapy,bronchoalveolar lavage and drug injection by bronchofibroscope were treated for patients in therapy group in addition.Therapeutic effects were compared between two groups. Result： There were 11 cases recovered in control group and 25 cases recovered in therapy group,The effective rates were significant difference between two groups（55% vs 87.5%,P〈0.05）.The hospitalization days and discharge costs in therapy group were lower than those in control group（P〈0.01）. Conclusion： Bronchoalveolar lavage and drug injection by bronchofibroscope is effective and safe for patients with refractory pneumonia,can reduce hospitalization days and discharge costs,deserving popularized.