经皮注射自体红骨髓治疗骨折延迟愈合及不愈合的疗效观察

The Effect of Autologous Bone Marrow Transplantation in Treating Delayed Union and Nonunion of Limb Fractures

目的:回顾分析经皮注射自体红骨髓治疗骨折延迟愈合及不愈合的疗效。方法:2006年1月至2009年1月之间本科收治的骨折延迟愈合或不愈合患者15例,在X线透视下定位穿刺将自体红骨髓注射至骨折断端,定期随访观察疗效。结果:15例均获随访,随访时间6-20个月,中位随访数为12个月。14例达到骨性愈合,愈合时间4-11个月,中位愈合数为6个月。1例患者为胫骨中下段骨折,注射3次后演变为骨不连,予以手术内固定、植骨后骨折愈合。结论:经皮注射自体红骨髓是治疗骨折延迟愈合及不愈合的一种操作简便、安全可靠的方法。

Objective： To investigate the effect of transcutaneous autologous bone marrow transplantation in treating delayed union and nonunion of limbs fractures. Method： Fifteen patients with delayed union or nonunion limb fractures were treated in our department between Jan.2006 and Jan.2009.All patients received transcutaneous autologous bone marrow transplantation,and were followed up to observe the effects. Result： The follow-up last from 6 to 20 months,average 12 months.14 of 15 patients were cured after 4-11 months,average 6 months.One patient suffered from nonunion,and then cured after bone grafting. Conclusion： Transcutaneous autologous bone marrow transplantation is a simple and effective method that can induce the osteogenesis in the delayed or nonunion fractures.