聚己内酯/聚乙烯吡咯烷酮共混物的亲水性和生物降解性

Properties of Hydrophilicity/Hydrophobicity and Biodegradation of Polycaprolactone/Polyvinylpyrrolidone Blends

用X-射线衍射、傅里叶变换红外光谱和扫描电镜方法对聚己内酯(PCL)/聚乙烯吡咯烷酮(PVP)共混物进行表征,并对共混物进行接触角测试和体外降解试验。结果表明:PVP的加入对PCL的晶型无影响,两者在共混过程中并未发生化学反应;随着PVP质量分数的增加,共混物与水的接触角减小,黏附功和浸湿功同步增大,3种参数都在PVP质量分数为15%处发生转折;PCL/PVP共混物降解质量损失率随PVP质量分数的增加而逐渐增大,且共混物的总质量损失逐渐由以PCL为主过渡到以PVP为主,脂肪酶加速了PCL/PVP共混物的降解速率。

The polycaprolactone （PCL）/polyvinylpyrrolidone （PVP） blends were characterized by X-ray diffraction （XRD）, infrared spectroscopy （FTIR）and scanning electron microscopy （SEM） and blends were used for contact angle measurement and in vitro degradation tests. The results showed that the contents of PVP could not influence PCL crystal type, only diluting the blends, and no chemical reaction in the blending process, with increasing PVP content, the water contact angle decreased, while the adhesion work and immersion wetting work increased synchronously, at the 15 % PVP content, all the three curves appeared inflection points, thereafter the curves changed sharply, the degradation weight loss rate of PCL/ PVP blends increases with increasing PVP content, and the total weight loss rates of the blend were gradu- ally transformed from PCL-dominated to PVP-dominated, the addition of lipase accelerates the PCL/PVP degradation rate.