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胶囊渗透压泵控释胰岛素样生长因子结合蛋白相关蛋白1对小鼠肝肺组织的影响 被引量:1

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摘要 胰岛素样生长因子结合蛋白相关蛋白1(insulin—like growth factorbinding protein—related proteinl,IGFBPrPl)是一种可溶性细胞黏附糖蛋白,主要在肝脏分泌,激活的肝星状细胞(HSC)是IGFBPrP1主要的来源细胞。Liu等发现IGFBPrPl是一种导致肝纤维化的新致病因子,那么IGFBPrPl对肝脏的损伤是否具有特异性呢?目前尚不清楚。动物腹腔注射给药时IGFBPrPl半衰期短,代谢快,
出处 《中华内科杂志》 CAS CSCD 北大核心 2011年第10期884-885,共2页 Chinese Journal of Internal Medicine
基金 国家自然科学基金(30871146) 山西省回国留学人员科研资助项目(2009-44)
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