内科保守联合介入治疗缺血性结肠炎的临床观察

Clinical study of medical expectant treatment combined with interventional treatment for ischemic colitis

目的观察内科保守联合介入治疗缺血性结肠炎的临床疗效。方法选择25例缺血性结肠炎患者随机分为单纯保守治疗组(A组,13例)和内科保守联合介入治疗组(B组,12例),比较治疗前后腹痛及便血转归情况、红细胞沉降率(ESR)、血细胞比容(HCT)及纤维蛋白原(FIB)指标。结果单纯保守治疗组较内科保守联合介入治疗组的腹痛持续时间[(91.23±31.17)h、(50.30±20.12)h]和便血持续时间[(64.62±16.64)h、(48.00±13.54)h]更长,差异有统计学意义(P<0.001);治疗前后红细胞沉降率,血细胞比容和纤维蛋白原指标变化在各自组内比较有明显改善,差异有统计学意义(P<0.01),而在两组间比较则无显著性差异(P>0.05)。结论与单纯保守治疗组比较,内科保守联合介入治疗组显著改善血液流变学,能更快缓解患者症状,并有可能改善预后。

Objective To investigate the clinical efficacy of medical expectant treatment combined with interventional treatment for ischemic colitis（IC）.Methods Twenty-five IC patients were randomly divided into two groups： medical expectant treatment group（group A,n=13） and medical expectant treatment combined with interventional treatment group（group B,n=12）.The clinical parameters and treatment results were compared in the two groups.Results The time of the symptom of abdominal pain and lower gastrointestinal hemorrhage in group A were longer than those in group B [（91.23±31.17）h vs（50.30±20.12）h,（64.62±16.64）h vs（48.00±13.54）h].There was significant difference in improving the symptom between the two groups（P〈0.001）.There was no significant difference in parameters of hemorheology（ESR,HCT,FIB） between two groups（P〈0.05）.Conclusion Medical expectant treatment combined with interventional treatment for IC significantly improves the outcome and maybe intervene prognosis.