局灶性皮层发育不良的临床病理及影像学特征
被引量:4
摘要
局灶性皮层发育不良(focal cortical dysplasia,FCD)是皮层发育的先天性局灶性畸形,多数因难治性癫痫而接受手术治疗,并于术后病理确诊。我们回顾性分析了7例FCD,结合文献对其临床病史、影像学表现、病理形态特点、免疫组织化学检测结果和预后进行讨论,分析FCD各亚型之间的相关性,以提高对FCD的认识。
出处
《中华病理学杂志》
CAS
CSCD
北大核心
2011年第9期630-631,共2页
Chinese Journal of Pathology
参考文献11
-
1Palmini A,Najm I,Avanzini G,et al.Terminology and classification of the cortical dysplasias.Neurology,2004,62 (6Suppl 3):S2-S8.
-
2Taylor DC,Falconer MA,Bruton CJ,et al.Focal dysplasia of the cerebral cortex in epilepsy.J Neurol Neurosurg Psychiatry,1971,34(4):369-387.
-
3Krsek P,Maton B,Korman B,et al.Different features of histopathological subtypes of pediatric focal cortical dysplasia.Ann Neurol,2008,63(6):758-769.
-
4Piao YS,Lu DH,Chen L,et al.Neuropathological findings in intractable epilepsy:435 Chinese cases.Brain Pathol,2010,20(5):902-908.
-
5Fauser S,Schulze-Bonhage A,Honegger J,et al.Focal cortical dysplasias:surgical outcome in 67 patients in relation to histological subtypes and dual pathology.Brain,2004,127 (Pt 11):2406-2418.
-
6Turkdogan D,Duchowny M,Resnick T,et al.Subdural EEG patterns in children with taylor-type cortical dysplasia:comparison with nondysplastic lesions.J Clin Neurophysiol,2005,22 (1):37-42.
-
7朴月善,陈莉,付永娟,王玮,李勇杰,卢德宏.癫痫相关局灶性皮质发育不良的临床病理学研究[J].中华病理学杂志,2007,36(3):150-154. 被引量:40
-
8Woermann FG,Vollmar C.Clinical MRI in children and adults with focal epilepsy:a critical review.Epilepsy Behav,2009,15(1):40-49.
-
9Bautista JF,Foldvary-Schaefer N,Bingaman WE,et al.Focal cortical dysplasia and intractable epilepsy in adults:clinical,EEG,imaging,and surgical features.Epilepsy Res,2003,55(1-2):131-136.
-
10Kim DW,Lee SK,Chu K,et al.Predictors of surgical outcome and pathologic considerations in focal cortical dysplasia.Neurology,2009,72(3):211-216.
二级参考文献15
-
1蔡立新,李勇杰.癫痫外科中双重病理的临床特点与手术治疗[J].立体定向和功能性神经外科杂志,2004,17(3):187-189. 被引量:14
-
2遇涛,李勇杰,王玉平,张国君,卢德宏,陈莉,蔡立新,杜薇.皮质发育不良导致的难治性部分性癫癎临床特征分析[J].中华神经科杂志,2006,39(3):148-151. 被引量:19
-
3Kuzniescky RI, Barkovich AJ. Malformations of cortical development and epilepsy. Brain Dev, 2001,23( 1 ) :2-11.
-
4Palmini A, Najm I, Avanzini G, et al. Terminology and classification of the cortical dysplasias. Neurology, 2004, 62 (6Suppl 3) :S2-S8.
-
5Rickert CH. Cortical dysplasia: neuropathological aspects. Childs Nerv Syst, 2006, 22(8) : 821-826.
-
6Fauser S, Schulze-Bonhage A, Honegger J, et al. Focal cortical dysplasias: surgical outcome in 67 patients in relation to histological subtypes and dual pathology. Brain, 2004, 127 ( Pt11 ) :2406-2418.
-
7Hildebrandt M, Pieper T, Winkler P, et al. Neuropathological spectrum of cortical dysplasia in children with severe focal epilepsies. Acta Neurepathol( Berl), 2005,110( 1 ) : 1-11.
-
8Kakita A, Kameyama S, Hayashi S, et al. Pathologic features of dysplasia and accompanying alterations observed in surgical specimens from patients with intractable epilepsy. J Child Neurel,2005, 20(4) : 341-350.
-
9Tassi L, Colombo N, Garbelli R, et al. Focal cortical dysplasia:neuropathological subtypes, EEG, neuroimaging and surgical outcome. Brain, 2002, 125(Pt 8) :1719-1732.
-
10Lawson JA, Birchansky S, Pacheco E, et al. Distinct clinicopathologic subtypes of cortical dysplasia of Taylor.Neurology, 2005, 64( 1 ) :55-61.
共引文献39
-
1陈莉,徐庆中,朴月善,张国君,遇涛,杨小平,杨虹,卢德宏.胚胎发育不良性神经上皮瘤与皮质发育不良[J].中华病理学杂志,2007,36(8):524-528. 被引量:13
-
2刘磊,朴月善,王玮,陈莉,隗立峰,杨虹,卢德宏.难治性癫痫相关局灶性皮质发育不良中NMDA受体及微小清蛋白阳性神经元的分布与表达[J].中华病理学杂志,2008,37(1):16-20. 被引量:2
-
3王玮,朴月善,刘磊,陈莉,隗立峰,杨虹,卢德宏.难治性癫痫患者脑组织中相关耐药蛋白表达情况的比较研究[J].中华病理学杂志,2008,37(1):21-26. 被引量:3
-
4蔡立新,朴月善,刘磊,卢德宏,李勇杰.局灶性皮质发育不良的脑电图特点与病理组织学改变相关性[J].中华神经科杂志,2009,42(2):110-114. 被引量:1
-
5孙福海,朴月善,王玮,陈莉,隗立峰,杨虹,卢德宏.难治性癫痫相关脑肿瘤的临床病理学研究[J].中华病理学杂志,2009,38(3):153-157. 被引量:10
-
6刘静,朴月善,卢德宏,王玮,陈莉,隗立峰,杨虹.难治性癫痫273例的临床病理学分析[J].中华神经科杂志,2009,42(10):676-681. 被引量:8
-
7王玮,朴月善,陈莉,卢德宏.难治性癫痫的神经病理学进展[J].中国神经精神疾病杂志,2009,35(12):751-753. 被引量:11
-
8刘静,卢德宏,朴月善,王玮,陈莉,隗立峰,杨虹.CD34在难治性癫痫相关脑肿瘤中的表达及鉴别诊断意义[J].中华病理学杂志,2010,39(3):151-155. 被引量:6
-
9单永治,赵国光,徐建堃,凌锋.脑皮质发育不良继发顽固性癫痫的病理分型及手术治疗[J].中华神经外科杂志,2010(3):206-208. 被引量:5
-
10王玮,朴月善,卢德宏,陈莉,隗立峰,杨虹.难治性癫痫相关耐药蛋白在局灶性皮质发育不良脑组织中的表达[J].中华神经科杂志,2010,43(7):473-478. 被引量:4
同被引文献32
-
1Taylor DC,Falconer MA, Bruton CJ, et al. Focal dysplasia of the cerebral cortex in epilepsy[J].J Neurol Neurosurg Psychiat, 1971,34(4) :369-387.
-
2Palmini A, Najm I, Avanzini G et al. Terminology and classifica- tion of the cortical dysplasias[J]. Neurology, 2004,62 (6 Suppl 3) : S2-S8.
-
3Beleza P. Refractory epilepsy a clinically oriented review[J]. Eur Neurol, 2009,62 (2) 65-71.
-
4Cepeda C, Andr6 VM, Levine MS, et al. Epileptogenesis in pedimric cortical dysplasia: the dysmature cerebral developmental hy- pothesis[J]. Epilepsy Behav, 2006,9 (2) : 219-235.
-
5Aronica E, Becker AJ, Spreafico R. Malformations of cortical de- velopment[J]. Brain Pathol, 2012,22 (3) : 380 401.
-
6Kral T, von Lehe M, Podlogar M, et al. Focal conical dysplasia: Long-term seizure outcome after surgical treatment[J]. J Neurol Neurosurg Psychiatry, 2007,78 (8) : 853-856.
-
7Saini J, Singh A, Kesavadas C, et al. Role of three-dimensional flu- id-attenuated inversion recovery (3D FLAIR) and proton density magnetic resonance imaging for the detection and evaluation of le- sion extent of focal cortical dysplasia in patients with refractory epilepsy[J]. Aeta Radiol,2010,51 (2) :218-225.
-
8Krsek P,Maton B, Jayakar P, et al. Incomplete resection of focal cortical dysplasia is the main predictor of poor postsurgieal out- come[J]. Neurology, 2009,72 (3) : 217-223.
-
9Colombo N, Tassi L, Galli C, et al. Focal cortical dysplasias: MR imaging, histopathologic, and clinical correlations in surgically treated patients with epilepsy[J]. AJNR Am J Neuroradiol,2003,24: 724-733.
-
10Kabat J, Kr61 P. Focal cortical dysplasia review[J]. Pol J Radiol, 2012,77:35-43.
引证文献4
-
1郭燕舞,张世忠,柯以铨,张新伟,张旺明,薛杉,谢韬,周谷兰,张柳.致痫性局灶性脑皮层发育不良患者的PET—CT与MRI研究[J].中华神经外科杂志,2013,29(1):7-11. 被引量:7
-
2周连银,郭燕舞,唐运林,柯以铨,张新伟,张奕生,徐越,王方伟,卞园园,袁金娥.致癇性局灶性皮层发育不良的外科治疗[J].华南国防医学杂志,2013,27(4):248-250. 被引量:1
-
3韩春,初曙光.局灶性皮质发育不良[J].中国临床神经科学,2013,21(3):364-364. 被引量:1
-
4党连荣,裴慧杰,王文娟,南雅炫,王文鹏.3.0T磁共振对癫痫患者颅脑检查诊断分析[J].甘肃医药,2021,40(8):729-731. 被引量:1
二级引证文献10
-
1孙恒,郝玉军.局灶性脑皮质发育不良与难治性癫痫的研究进展[J].中华神经外科杂志,2015,31(11):1186-1188. 被引量:6
-
2田春雷,王晓丹,王雄伟.局灶性皮层发育不良与mTOR信号通路[J].中国临床神经外科杂志,2016,21(2):122-124. 被引量:1
-
3尤玉娟.脑电图-功能磁共振成像技术对局灶性癫痫致痫灶定位的价值分析[J].甘肃医药,2016,35(5):367-368. 被引量:2
-
4王倩.104例癫痫患者头颅CT和MRI对比分析[J].现代医用影像学,2017,26(4):1004-1005. 被引量:1
-
5郑重,李俊驹,张建国,桑林,周峰,解飞,马延山,张凯,刘焕光,姜胤.局灶性皮质发育不良所致难治性癫痫的手术预后影响因素分析[J].中华神经外科杂志,2018,34(3):268-272. 被引量:13
-
6魏强,边艳珠,胡玉敬,田丛娜,吴大勇,康林.统计参数图用于^(18)F-FDGPET定位局灶性脑皮层发育不良所致难治性癫痫致痫灶[J].中国医学影像技术,2018,34(8):1169-1172. 被引量:4
-
7苏富勇,刘健.PET/MRI在癫痫灶定位中的临床应用分析[J].医学影像学杂志,2018,28(11):1799-1802. 被引量:2
-
8张亚超,乔辉,李泽,李鹏.脑电图、磁共振和PET-CT对继发性癫痫患者致痫灶的诊断价值[J].放射学实践,2019,34(12):1390-1393. 被引量:24
-
9党连荣.海马硬化致颞叶癫痫的临床及磁共振成像诊断[J].癫痫杂志,2022,8(4):316-319. 被引量:2
-
10王舒扬,丁晶,汪昕.局灶性皮质发育不良致■机制研究进展[J].中国临床神经科学,2022,30(6):661-667.
-
1田春雷,王晓丹,王雄伟.局灶性皮层发育不良与mTOR信号通路[J].中国临床神经外科杂志,2016,21(2):122-124. 被引量:1
-
2郝改领,娄燕.NF-κB(P65)在小儿局灶性皮层发育不良(FCD)Ⅲa中的表达分析[J].世界最新医学信息文摘,2015,0(93):6-8.
-
3陈述花,王静,刘兴洲,闫兆芬,林娟霞.头皮脑电图在不同类型局灶性皮层发育不良所致难治性癫痫中的定位价值[J].癫痫与神经电生理学杂志,2014,23(2):69-74. 被引量:1
-
4赵殿江,朱明旺,杜铁桥,王大堃.局灶性脑皮层发育不良的MRI诊断[J].临床放射学杂志,2009,28(10):1358-1361. 被引量:7
-
5谷智明.不同局灶性皮层发育不良病理分型颞叶癫痫患者临床特征比较[J].临床和实验医学杂志,2017,16(1):32-34. 被引量:2
-
6王江娅,李文玲,武江,赵焕芬,毛金丽,娄燕.38例儿童颞叶难治性癫痫病理分析[J].临床儿科杂志,2015,33(3):265-268. 被引量:5
-
7王江娅,李文玲,武江,娄燕.信号转导与转录活化因子3在儿童颞叶局灶性皮层发育不良Ⅲa型中的表达[J].临床儿科杂志,2014,32(9):859-862.
-
8何春年,赵文清,李萍,李文玲,赵焕芬,翟金萍,孙吉林.癫痫患者切除病灶病理学分析[J].中国临床神经外科杂志,2008,13(9):524-526. 被引量:7
-
9亚静.难治性癫痫有望找到治疗新方法[J].家庭医药(就医选药),2015,0(10):4-4.
-
10梅开勇,郝卓芳,欧阳小明,李明昌,练辉.脑局灶性皮层发育不良相关性难治性癫痫的临床病理分析[J].中国神经精神疾病杂志,2010,36(7):419-422. 被引量:5