女性阴道微生态变化与两种阴道炎的关系

Relationship of microecological environmental changes of vagina and two kinds of vaginitis

目的了解外阴阴道假丝酵母菌病(VVC)及滴虫性阴道炎(TV)与阴道微生态情况的关系。方法用常规检测和细菌性阴道病(BV)三联法(BVset)测定2380例VVC(VVC组)、1399例TV患者(TV组)和648例正常体检者(对照组)阴道分泌物中过氧化氢(H2O2)浓度、唾液酸苷酶和白细胞酯酶活性。结果 VVC和TV患者三联法检测白细胞酯酶阳性率分别为34.7%和61.5%,明显高于对照组的6.6%(P<0.05);且TV组的白细胞酯酶阳性率显著高于VVC组(P<0.05)。结论 VVC和TV的发生与阴道微生态环境的失衡密切相关;对患者进行白带常规检测的同时进行BVset尤其是白细胞酯酶活性测定,能更好地反映出患者阴道微生态状况,对控制阴道炎的复发有一定的指导意义。

Objective To investigate the relationship of microecological environment of vagina and vulvovaginal candidiasis（VVC） and trichomonas vaginitis（TV） of women.Methods The examinations of hydrogen peroxide,sialidase and leukocyte esterase in vaginal secretions were performed with routine smear and BV triple test in 2380 cases with VVC （group VVC）,1399 cases with TV（group TV） and 648 healthy controls（group C）.Results The positive rates of leukocyte esterase in groups of VVC and TV were 34.7% and 61.5%,respectively,which were both higer than 6.6% in group C（P0.05）.The positive rate was higher in group TV than that in group VVC（P0.05）.Conclusion The occurance of VVC and TV is closely related to the unbanlance of vaginal microecological environment.Examining vaginal secretions with routine smear and BVset,especially with leukocyte esterase test,should be taken for guiding the microecological evaluation and controlling the recurrence of vaginitis.