角膜上皮擦伤致复发性角膜上皮糜烂临床分析

Clinical analysis of secondary recurrent corneal erosion caused by corneal abrasion

目的分析角膜上皮擦伤所致继发性复发性角膜上皮糜烂的临床特征,为其诊断和治疗提供一定的帮助。方法回顾性分析9例角膜上皮擦伤所致继发性复发性角膜上皮糜烂患者的临床资料,包括患者病史、一般情况、临床特点、诊断与治疗及预后等。结果 9例患者中男4例,女5例;年龄18～51岁;初次发作距角膜外伤的时间间隔为2～24周,平均(8.8±6.5)周。致伤物分别为手指、眼镜、塑料、纸片等。典型的症状表现为早晨醒时或夜晚睡眠时突然发病,患眼出现疼痛、眼红、流泪、畏光、异物感等刺激症状。5例行保守治疗,4例行手术治疗;角膜上皮完全愈合时间为1～10d。未见严重眼部并发症。结论角膜上皮擦伤致继发性复发性角膜上皮糜烂具有典型的临床特征,表现为早晨睡醒或睡眠时突然发作的眼部刺激征,且有反复发作的特点,部分多次反复发作的患者需要手术治疗。该病的预后良好。

Objective To investigate the clinical features of secondary recurrent corneal erosion caused by corneal abrasion and to study the diagnosis and treatment of this disorder.Methods The clinical data of 9 cases of secondary recurrent corneal erosion caused by corneal abrasion were retrospective analyzed.Results Among the 9 cases,4 were males,and 5 were females.The patients＇ age ranged from 18 to 51 years.The interval between the initial episode and corneal trauma was from 2 weeks to 24 weeks with average of（8.8±6.5） weeks.The vulnerant included finger,glasses,plastics and paper.Typical symptoms was sudden onset on morning wakening or sleeping at night,suffering from irritation of eye pain,redness,tearing,foreign body sensation and photophobia.Five cases underwent conservative treatments,and 4 cases underwent surgical treatments.Complete healing of corneal epithelium was from 1 to 10 days.No serious ocular complications were observed.Conclusions Secondary recurrent corneal erosion caused by corneal abrasion has clinical character showed typical features including the sudden onset on morning waking or sleeping at night,and with recurrent eye irritation.Some patients with more repeated attack required surgery.This disease had a good prognosis.