全景超声生物显微镜对人眼睫状沟距离及前房直径的测量

Correlation between anterior chamber angle diameter and ciliary sulcus distance measured by Suowei panoramic 50-MHz digital ultrasound biomicroscopy

背景睫状沟距离的直接测量对人工晶状体（IOL）植人术中IOL尺寸的选择具有重要意义。全景超声生物显微镜（UBM）的问世使在活体眼直接进行睫状沟距离的测量成为可能。目的探讨人眼前房直径和睫状沟距离之间的相关性及其在不同前房深度人群中的差别。方法将疑似青光眼患者30例30只右眼作为浅前房组，而具有高度近视（-7— -18D）的30例30只右眼作为深前房组。应用全景超声生物显微镜（UBM）进行图像采集，每眼获取焦点位于虹膜平面的眼球水平方向3：00～9：00处的全景截面图像共3张。由同一测量者对每一幅图像的前房直径和睫状沟距离进行测量。取3幅图像测量值的均值为最终测量结果，用独立样本t检验和线性回归方程分析评估前房直径与睫状沟距离测量值的关系。结果浅前房组的30眼中，全景UBM测得的前房直径为（11．49±0．75）mm，睫状沟距离为（10．97±0．86）mm，二者间的平均差值为（-5．14±0．55）mm，差异有统计学意义（t=-5．092，P=0．000），线性回归分析显示二者之间呈线性相关（R2=0．593，P=0．000），Pearson相关系数为0．767。深前房组的30眼中，全景UBM测得的前房直径均值为（12．69±0．67）mm；睫状沟距离为（12．31±0．61）mm，二者之间平均差值为（-0．38±0．17）mm，差异有统计学意义（t=-5．531，P=0．000）；线性回归分析显示二者之间具有显著相关性（R2=0．699，P=0．000），Pearson相关系数为0．836。结论全景UBM测得的睫状沟距离和前房直径呈明显正相关，深前房眼的相关性大于浅前房眼，该结果对于IOL植入术中IOL尺寸的选择具有重要意义。

Background Measurement of ciliary sulcus distance is important for phakic intraocular lens implantation. Suowei panoramic 50-MHz digital ultrasound biomicroscopy makes it possible for the direct measurement of ciliary sulcus distance. Objective The aim of this study was to investigate the correlation between anterior chamber （AC） angle diameter and ciliary sulcus distance in different AC depth population and offer a clinical guide. Methods The anterior chamber angle diameter and ciliary sulcus distance were measured in 30 right eyes with shallow anterior chamber caused by suspect glaucoma and 30 right eyes with deep anterior chamber dut to the high myopia with Suowei panoramic 50-MHz digital ultrasound biomicroscopy. Three horizontal B-scans with the focal plane approximately at a depth corresponding to the iris plane were acquired for each eye. The differences of the anterior chamber angle diameter and ciliary sulcus distance were calculated and compared between the two groups. The correlation of the anterior chamber angle diameter and ciliary sulcus distance were evaluated in respective group. Results In shallow AC group,the mean angle diameter was （1 l. 49±0.75 ）ram,the mean ciliary sulcus distance was （10. 97±0. 86）mm with the mean standard deviation of the difference of （-5. 14±0. 55 ）ram, showing a statistically significant difference （t =-5. 092, P = 0. 000）. In shallow AC group, linear regression analysis showed a statistically significant correlation between ciliary suleus distance and angle diameter （R2 = 0. 593 ,P = 0. 000） and the Pearson＇ s correlation coefficient was 0. 767. In deep AC group, the angle diameter was （ 12.69±0.67 ）mm ; while ciliary sulcus distance was （12.31±0.61） mm with the mean standard deviation （-0.38±0. 17） ram,which was statistically significantly different （t =-5.531, P= 0. 000 ）. The ciliary sulcus distance was fbund to be linear correlation with the angle diameter （ R2 = 0. 699,P = 0. 000） and Pearson＇ s correlation coefficient of 0. 836. Conclusions Panoramic ultrasound biomicroscopy is an useful tool to the measurement of ciliary sulcus distanee. This study exhibited that the ciliary sulcus distance is significant associated with the anterior chamber angle diameter,which may offer a guide for phakic intraocular lens implantation.