摘要
目的:观察萘替芬酮康唑乳膏治疗儿童花斑糠疹的疗效及安全性。方法:129例儿童花斑糠疹患儿随机分为两组,治疗组67例,对照组62例,两组在病程、性别、年龄上无统计学差别;治疗组每天外搽萘替芬酮康唑乳膏2次,对照组外搽酮康唑乳膏2次,两组疗程均6周。于治疗前、治疗结束后分别记录患儿皮损情况、真菌检查及有无不良反应。结果:治疗组的有效率为92.54%,对照组的有效率为74.19%,治疗组和对照组比较疗效有统计学差异。治疗组的真菌清除率为98.51%,对照组的真菌清除率为90.32%,治疗组和对照组真菌清除率比较有统计学差异。两组患儿均无明显不良反应发生。结论:萘替芬酮康唑乳膏治疗儿童花斑糠疹安全有效。
Objective:To observe the efficacy of naftifine/ketoconazole cream in the treatment of pityriasis versicolor in children.Methods: 129 cases with pityriasis versicolor in children were divided into two groups randomly.Patients in the treatment group were given topical naftifine/ketoconazole cream twice daliy;patients in the control group were given topical ketoconazole cream twice daliy.The therapy lasted six weeks.Results: At the end of treatment,the response rate in the treatment group was 92.54%,and that in the control group was 74.19%.The fungal clearance rate in the treatment group was 98.51%,and that in the control group was 90.32%.There was significant difference between the treatment group and the control group.No significant adverse events were found.Conclusion: Naftifine/ketoconazole cream is effective and safe in the treatment of pityriasis versicolor in children.
出处
《川北医学院学报》
CAS
2011年第5期401-403,共3页
Journal of North Sichuan Medical College
基金
国家自然科学基金项目(31100020)
四川省科技厅项目(2009JY0123)
关键词
花斑糠疹
萘替芬
酮康唑
儿童
Pityriasis versicolor
Naftifine
Ketoconazole
Children