高能聚焦超声治疗宫颈糜烂198例临床观察

Clinical observation on high intensity focused ultrasound in treatment of cervical erosion in 198 cases

目的研究高能聚焦超声治疗宫颈糜烂的有效性及安全性。方法随机选择2006年1月至2009年1月我院妇科门诊经妇科检查,细胞学及阴道镜诊断、病理改变确诊为轻度、中度、重度宫颈糜烂患者共198例,采用高能聚焦超声治疗技术治疗,观察其临床疗效及副反应。结果轻度、中度、重度宫颈糜烂患者的治愈率和有效率分别为:94.12%/100%、69.74%/97.37%、38.89%/83.33%,宫颈糜烂程度越轻治愈率越高,轻度、中度糜烂治愈率明显高于重度糜烂(P<0.01);单纯型、颗粒型、乳头型宫颈糜烂患者的治愈率和有效率分别为:82.98%/100%、70.00%/81.43%、32.35%/76.47%,宫颈糜烂单纯型和颗粒型治愈率明显高于乳头型(P<0.01)。无严重的不良并发症。治疗后宫颈恢复常态,无瘢痕形成。结论高能聚焦超声治疗慢性宫颈炎具有安全可靠、治愈率高、创伤小、副作用小等特点,值得推广。

Objective To investigate the security and feasibility of high intensity focused ultrasound（HIFU） in the treatment of cervical erosion.Methods Totally 198 women with mild,moderate and severe cervical erosion diagnosed through gynecologic and cytological examinations as well as vaginoscope in our hospital from January 2006 to January 2009 were enrolled randomly.The clinical efficacy and side effects of HIFU were observed.Results Recovery and effective rates of mild,moderate and severe erosions were 94.12%/100%,69.74%/97.37% and 38.89%/83.33% respectively.The effective rates of mild and moderate erosion were significantly higher than those of severe type（P0.01）.Recovery and effective rates of simple,granular and mastoid erosions were 82.98% / 100%,70.00% / 81.43% and 32.35% / 76.47% respectively.The effective rates of simple and granular erosion were significantly higher than those of mastoid type（P0.01）.There was no severe complication and scar formation and the uterine neck returned to normal patterns postoperatively.Conclusion HIFU is safe and effective with fewer side effects;therefore it is worth promoting in clinics.