402例烟雾病抗核抗体谱检测结果分析

Analysis of the Results of Antinuclear Antibody Spectrum for Patients of Moyamoya

目的:探讨烟雾病的发生与自身免疫性疾病是否存在一定的联系。方法:对402例烟雾病抗核抗体谱检测结果进行回顾性分析。结果:402例烟雾病确诊病例中,有112位患者抗核抗体谱检测结果中存在阳性结果,阳性率为27.86%。其中,抗dsDNA、抗CB、抗Sm、抗SS-A、抗SS-B、抗Jo-1、抗RO-52、抗ScL-70、抗RIB、抗PM-sd、抗nRNP、抗PCNA、抗Nuc、抗HI、抗M2抗体在阳性病例中所占百分比分别为16.07%、1.79%、5.36%、17.86%、7.14%、5.36%、13.39%、5.36%、7.14%、4.46%、2.68%、11.61%、6.25%、8.93%和8.04%。结论:烟雾病患者中抗核抗体阳性率较高,自身免疫性疾病可能是烟雾病发生的重要诱因之一。

Objective： Look for the occurrence of moyamoya disease with autoimmune diseases was the existence of certain links.Methods： 402 cases of moyamoya disease spectrum antinuclear antibody test results were analyzed respectively.Results： 112 cases of anti-nuclear antibody spectrum result was positive in 402 cases of moyamoya disease,the positive rate was 27.86%,and the percentage of anti-dsDNA,anti-CB,anti-Sm,anti-SS-A,anti SS-B,anti Jo-1,anti-RO-52,anti-ScL-70,anti-RIB,anti-PM-sd,anti-nRNP,anti-PCNA,anti-Nuc,anti-HI and anti-M2 antibodies were 16.07%,1.79%,5.36%,17.86%,7.14%,5.36%,13.39%,5.36%,7.14%,4.46%,2.68%,11.61%,6.25% and 8.93%,8.04%,respectively.Conclusion： Autoimmune disease may be one of the causes of moyamoya disease.