雪莲化学成分和药理活性研究进展

Advances in studies on chemical components and pharmacological activites of Saussureae Involucratae Herba

雪莲是我国珍稀名贵的中药材,有着久远的药用历史以及丰富的民间用药基础。雪莲中含有的黄酮及其苷、倍半萜内酯、香豆素、木脂素、有机酸、氨基酸、甾体、多糖等成分,具有抗风湿、镇痛、调节心血管系统、抗癌、延缓衰老、计划生育、防辐射等生物活性,有很大的开发利用价值,应用前景良好。对药用雪莲近十年国内外的化学和药理活性研究进展进行综述,探讨雪莲临床用药中的依据,并对今后的研究方向进行了展望。

Saussureae Involucratae Herba, a rare Chinese medicinal herb grown in Xinjiang Uygur Autonomous Region of China, has a long history and the basis of folk medicine usage. The plants mainly contain chemical constituents belonging to flavonoids, sesquiterpene lactones, coumarins, lignans, organic acids, amino acids, steroids, and polysaccharides. Their chemical constituents possess the important biological activities, such as anti-rheumatic, analgesic, regulating the cardiovascular system, anticancer~ postponing senility, family planning, anti-radiation. The research development around the chemical constituents and biological activities in the latest ten years is reviewed and the clinical basis and development ofSaussureae Involucratae Herba are explored in this paper.