摘要
目的:分析医院2010年药品不良反应(ADR)发生的特点与规律,为临床合理用药提供参考。方法:对2010年1-12月收集的186例有效ADR报告进行分析。结果:186例ADR报告中,男性所占比例(55.38%)略高于女性(44.62%);中老年人所占比例最高(25.27%);引起ADR的主要用药途径为静脉给药(93.55%);由抗感染药物引起的ADR最多,占61.29%;累及器官/系统以皮肤及附件最为常见,占44.62%。结论:应加强与重视医院药品ADR的监测工作,避免或减少ADR的发生,使临床用药更为合理。
Objective: To learn the occurrence characteristics of adverse drug reactions (ADRs) in our hospital and to provide reference for rational clinical drug use. Methods: 186 ADR reports were collected in our hospital in 2010 and analyzed retrospectively. Results: Of the total 186 cases,the ADR reports of male and female were 55.38% and 44.62% respectively, among which the old took the highest proportion (25.27%), 93.55% of ADRs were induced by the drugs of intravenous administration. Anti-infective agent induced-ADRs were 61.29% and the rriost common clinical manifestations were the damage of skin and adnexa, which accounted for 44.62 %. Conclusion: Supervision of ADRs should be strengthened to improve the rational administration of drugs and to avoid or reduce ADR incidences.
出处
《中国执业药师》
CAS
2011年第10期7-8,13,共3页
China Licensed Pharmacist
关键词
药品不良反应
合理用药
抗感染药物
Adverse Drug Reaction
Rational Use of Drugs
Anti-Infective Agents