我院2010年186例药品不良反应报告分析

Analysis of 186 Case ADR Reports in Our Hospital in 2010

目的:分析医院2010年药品不良反应(ADR)发生的特点与规律,为临床合理用药提供参考。方法:对2010年1-12月收集的186例有效ADR报告进行分析。结果:186例ADR报告中,男性所占比例(55.38%)略高于女性(44.62%);中老年人所占比例最高(25.27%);引起ADR的主要用药途径为静脉给药(93.55%);由抗感染药物引起的ADR最多,占61.29%;累及器官/系统以皮肤及附件最为常见,占44.62%。结论:应加强与重视医院药品ADR的监测工作,避免或减少ADR的发生,使临床用药更为合理。

Objective： To learn the occurrence characteristics of adverse drug reactions （ADRs） in our hospital and to provide reference for rational clinical drug use. Methods： 186 ADR reports were collected in our hospital in 2010 and analyzed retrospectively. Results： Of the total 186 cases,the ADR reports of male and female were 55.38% and 44.62% respectively, among which the old took the highest proportion （25.27%）, 93.55% of ADRs were induced by the drugs of intravenous administration. Anti-infective agent induced-ADRs were 61.29% and the rriost common clinical manifestations were the damage of skin and adnexa, which accounted for 44.62 %. Conclusion： Supervision of ADRs should be strengthened to improve the rational administration of drugs and to avoid or reduce ADR incidences.