妊娠滋养细胞肿瘤180例临床疗效分析

Analysis on the clinical efficacy of 180 cases with gestational trophoblastic tumor

目的:分析滋养细胞肿瘤的规范化治疗及效果。方法:对1990～2008年收治的180例滋养细胞肿瘤患者的临床资料进行回顾性分析。结果:180例滋养细胞肿瘤患者平均年龄为31.8岁,126例患者行单纯化疗,54例患者行化疗加手术治疗。75例绒毛膜上皮癌的治愈率是79.45%,105例侵蚀性葡萄胎的治愈率是90.47%。结论:滋养细胞肿瘤患者首次化疗规范、足量并坚持巩固化疗,合理选择手术时机是影响滋养细胞肿瘤预后的重要因素。

Objective：To analyze the standard therapy and efficacy of gestational trophoblastic tumor. Methods：The clinical data of 180 patients with gestational trophoblastic tumor who were treated in the hospital from 1990 to 2008 were analyzed retrospectively. Results：The average age of 180 patients with gestational trophoblastic tumor was 31.8 years,126 patients were treated with simple chemotherapy,while the other 54 patients were treated with chemotherapy plus surgery.The curative rate of 105 patients with invasive hydatidiform mole was 90.47%. Conclusion：The important effect factors of prognosis of patients with gestational trophoblastic tumor are standard and insistent primary chemotherapy with full dose and reasonable surgical opportunity.