两种不同抗原制备方法对大肠杆菌O_(157):H_7单克隆抗体亚类的影响
摘要
单克隆抗体技术已深入到医学和生物学的各个领域,成为一种必不可少的工具,具有极为重要的理论研究价值和实用价值。据报道,全菌抗原的主要抗原位点是脂多糖(LPS),刺激机体产生的IgG抗体主要针对脂多糖,故不同血清型间无交叉保护作用;
出处
《黑龙江畜牧兽医》
CAS
北大核心
2011年第10期129-130,共2页
Heilongjiang Animal Science And veterinary Medicine
参考文献5
-
1张燕,卢思奇,张永振,赵斌秀,徐建国.O157:H7大肠杆菌外膜蛋白对小鼠免疫保护作用的实验研究[J].中华医学杂志,2004,84(1):58-62. 被引量:9
-
2徐志凯.实用单克隆抗体技术[M].西安:陕西科学技术出版社,1992.177-190.
-
3魏燕玲.单克隆抗体ELISA检测产毒大肠杆菌不耐热肠毒素LT的应用研究[J].中国人兽共患病杂志,1988,4(3):5-5.
-
4PASCALE J M, SHAW M M, DURANT P J, et al. Intranasal immunization confers protection against murine Pneumocysis carinii lung infection[ J]. Infect Immun, 1999, 67:805 - 809.
-
5RUDIN A, JOHANSSON E L, BERGQUIST C, et al. Differential kinetics and distribution of antibodies in serum and nasal and vaginal secretions after nasal and oral vaccination of human [ J ]. Infect Immun, 1998, 66:3390 - 3396.
二级参考文献11
-
1Konadu E, Donohue-Rolfe A, Calderwood SB, et al. Syntheses and immunologic properties of Escherichia coli O157 O-specific polysaccharide and Shiga toxin 1 B subunit conjugates in mice. Infect Immun, 1999, 67:6191-6193.
-
2Dean-Nystrom EA, Gansheroff LJ, Mills M, et al. Vaccination of pregnant dams with intimin(O157) protects suckling piglets from Escherichia coli O157:H7 infection. Infect Immun, 2002, 70:2414-2418.
-
3Gansheroff LJ, Wachtel MR, O'Brien AD. Decreased adherence of Enterohemorrhagic Escherichia coli to Hep-2 cells in the presence of antibodies that recognize the C-terminal region of Intimin. Infect Immun, 1999, 67: 6409-6417.
-
4Sherman PM, Soni R. Adherence of Vero cytotoxin-producing Escherichia coli of serotype O157:H7 to human epithelial cells in tissue culture: role of outer membranes as bacterial adhesins. J Med Microbiol, 1988, 26:11-17.
-
5Achtman M, Mercer A, Kusecek B, et al. Six Widespread Bacterial Clones Among Escherichia coli K1 Isolates. Infect Immun, 1983, 39:315-335.
-
6Pascale JM, Shaw MM, Durant PJ, et al. Intranasal immunization confers protection against murine Pneumocysis carinii lung infection. Infect Immun, 1999, 67:805-809.
-
7Rudin A, Johansson EL, Bergquist C, et al. Differential kinetics and distribution of antibodies in serum and nasal and vaginal secretions after nasal and oral vaccination of human. Infect Immun, 1998, 66:3390-3396.
-
8Conlan JW, Cox AD, KuoLee R, et al. Parenteral immunization with a glycoconjugate vaccine containing the O157 antigen of Escherichia coli O157:H7 elicits a systemic humoral immune response in mice, but fails to prevent colonization by the pathogen. Can J
-
9Michetti P, Mahan MJ, Slauch JM, et al. Monoclonal secretory immunoglobulin A protects mice against oral challenge with the invasive pathogen Salmonella typhimutium. Infect Immun, 1992, 60:1786-1792.
-
10Phalipon A, Kaufmann M, Michetti P, et al. Monoclonal Immunoglobulin A antibody directed against Serotype-specific epitope of Shigella flexneri lipopolysaccharide protects against murine experimental shigellosis. J Exp Med, 1995, 182:769-778.
共引文献93
-
1涂小萍,秦敏,杨国友,杨勇,周富昌,赵彬,刘瑛.幽门螺杆菌尿素酶单克隆抗体的研制及鉴定[J].微生物学免疫学进展,2004,32(3):26-29. 被引量:2
-
2许文革,刘一兵,韩世泉,胡轶丁,罗志福.抗SARS冠状病毒表面抗原抗体的制备及其初步应用[J].原子能科学技术,2005,39(2):101-105.
-
3贲松彬,赵洪礼,聂晶,宋承辉,董萍,王军.早期诊断肾综合征出血热自身红细胞凝集试验[J].中国公共卫生,2005,21(3):329-330.
-
4朱学泰,谢溱,马亚茹,马瑞君.抗KDR-Fc杂交瘤细胞系的建立[J].西北师范大学学报(自然科学版),2005,41(3):71-74.
-
5唐玮,王鲁,唐书谦,钟白玉,叶庆佾.单抗Mab03.2C1C2影响白念珠菌芽管形成及粘附作用的实验研究[J].第三军医大学学报,2005,27(9):901-903. 被引量:3
-
6金晓航,黄威权,夏永娟,李元,李别虎.迟缓爱德华菌抗独特型单克隆抗体的制备及鉴定[J].水生生物学报,2005,29(3):340-343. 被引量:13
-
7彭军,李宝全,沈志勇,王建昌,宁海强,牛钟相.用间接ELISA检测抗H9亚型AIV独特型单克隆抗体的研究[J].免疫学杂志,2005,21(B06):119-121.
-
8宋秋荷,王鲁,郝飞,唐书谦,钟白玉,叶庆佾.酵母菌烯醇化酶单克隆抗体的制备及鉴定[J].第三军医大学学报,2005,27(13):1329-1331. 被引量:3
-
9唐勇,向军俭,罗辉武,邓宁,王宏.重金属镉离子单克隆抗体的制备[J].食品科学,2005,26(9):350-353. 被引量:18
-
10王平,黄庆生,丁天兵,任君萍,宋建华,徐志凯.SARS冠状病毒囊膜E蛋白的重组表达与单克隆抗体制备[J].生物技术通讯,2005,16(5):485-487.
-
1黄显明,张小飞,魏建忠,李春芬,廖俊伟.Ⅰ型鸭病毒性肝炎研究进展[J].动物医学进展,2007,28(11):78-81. 被引量:7
-
2马树红,武桂鑫,李志鹏.当前鸡传染性支气管炎的特点及防治[J].当代畜牧,2006,35(11):11-12.
-
3赵军丽,陈金海,陈金敏.鸡传染性支气管炎的特点与防制[J].养殖与饲料,2009,8(11):28-29.
-
4李炽新,吴国胜,陈振明,陈根植.猪肺疫AB二联活疫苗试验[J].广东畜牧兽医科技,2004,29(5):43-44. 被引量:2
-
5范卫国,杜佳慧,曹瑞兵,陈溥言.Ⅰ型鸭肝炎病毒概述[J].动物医学进展,2009,30(11):110-114. 被引量:15
-
6周会明,柴红梅,赵永昌.田头菇属真菌研究进展[J].中国食用菌,2009,28(6):3-8. 被引量:7
-
7张国广,邹金美,张辉煌,董美,陈亮.H5N1亚型禽流感病毒M2的修饰表达及其免疫原性分析[J].漳州师范学院学报(自然科学版),2009,22(3):134-138.
-
8杨先进.蓝耳病疫苗的交叉保护性得到证实[J].中国兽药杂志,2001,35(3):60-61. 被引量:3
-
9钱晨,高巍,姚太平.鸡肾型传染性支气管炎病毒的分离与鉴定[J].中国家禽,2010,32(22):47-48. 被引量:1
-
10刘平平.禽流感灭活油乳剂疫苗的交叉保护作用[J].山东畜牧兽医,2015,36(1):26-27.