颈动脉粥样硬化与脑梗死复发临床关系探讨

The clinical relationship between carotid atherosclerosis and recurrence of cerebral infarction

目的探讨颈动脉粥样硬化与脑梗死复发的关系。方法收集脑梗死住院患者241例,通过颈动脉彩超检查颈动脉粥样硬化情况,随访观察有无脑梗死复发。结果 241例脑梗死患者有23例复发性脑梗死,脑梗死复发和未复发患者颈动脉斑块检出率差异无统计学意义(P>0.05);复发脑梗死患者颈总动脉、颈动脉分叉处血管内中膜厚度值(CCA-IMT、ICA-IMT、BIF-IMT)明显高于未复发患者(P<0.01)。结论颈动脉内中膜厚度增厚患者脑梗死复发率增高。

Objective To investigate the relationship between carotid atherosclerosis（CAS） and recurrence of cerebral infarction（CI）.Methods We consecutively recruited 241 patients with acute cerebral infarction,and ultrasonography was performed to evaluate the situation of CAS.All patients were followed up prospectively and the outcome of recurrence of cerebral infarction was observed.Results Among 241 patients with CI,recurrence was seen in 23 of them.The frequency of plaque occurred in carotid artery among patients with recurrence of CI or free of recurrence of CI had no significant difference（P0.05）.Frequency of occurrence of soft plaque,complex plaque and values of intima-media thickness（CCA-IMT,ICA-IMT,BIF-IMT） were higher in patients with recurrence of CI than those with free of CI recurrence（P0.01）.Conclusion Increased IMT values are associated with a higher risk of long-term stroke recurrence.