硫酸钴-乙酸协同催化醇和酚的四氢吡喃化反应(英文)

Cobalt Sulfate-Acetic Acid as a Novel Synergistic Catalytic System for Tetrahydropyranylation of Alcohols and Phenols

报道了硫酸钴-乙酸在室温、无溶剂条件下催化醇和酚的四氢吡喃化反应。硫酸钴-乙酸作为协同催化体系,二者缺一不可。与传统催化剂相比,新催化体系的催化活性最好.反应结束后,硫酸钴经简单相分离可回收,重复使用多次催化活性无明显下降。提出了可能的催化反应机理.

Cobalt sulfate-acetic acid is found to catalyze the tetrahydropyranylation of alcohols and phenols efficiently at room temperature under solvent-free conditions. It is a synergistic catalytic system, and both cobalt sulphate and acetic acid are indispensable for the rate acceleration of the reaction. Compared with other conventional catalysts, cobalt sulphate-acetic acid proved to be the best. After reaction, cobalt sulphate can be easily recovered by simple phase-separation and reused for many times without deterioration in catalytic activity. A probable reaction mechanism is proposed.