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ATP-TCA在肿瘤治疗中的临床应用进展 被引量:1

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摘要 目的:了解三磷酸腺苷(ATP)生物荧光肿瘤体外药物敏感性检测技术(ATP-TCA)在临床中的应用情况。方法:对ATP-TCA法在多种肿瘤化疗方案筛选中的应用情况进行综述,包括卵巢癌、乳腺癌、非小细胞肺癌、消化道肿瘤、白血病、黑色素瘤、膀胱癌及口腔癌等。结果:ATP-TCA虽然存在一定的假阴性或假阳性,但在选择化疗方案时,将ATP-TCA结果作为一个重要参考因素,可以降低无效治疗的风险,制订出更适合患者的个体化化疗方案。结论:与其他肿瘤体外敏感性检测方法比较,ATP-TCA法具有突出优点,在临床应用前景良好,对肿瘤患者的个体化治疗具有重要价值。
作者 刘广军
出处 《中国药房》 CAS CSCD 北大核心 2011年第42期4007-4010,共4页 China Pharmacy
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