同型半胱氨酸检测在无传统危险因素引起的心脑血管疾病中的应用

Clinical implication of homocysteine detection in patients of CVD without high risk factor

目的探讨同型半胱氨酸(HCY)在无传统危险因素的心脑血管性疾病中的应用价值。方法采用荧光技术来检测心脑血管疾病患者(排除传统危险因素)和正常对照者各40例血浆中HCY的水平。结果心脑血管疾病组血浆HCY的水平明显高于对照组(P<0.01)。结论高HCY是心脑血管疾病的独立危险因子。HCY与心脑血管疾病的发生和发展可能有直接关系。检测HCY水平对预防和减低心脑血管疾病的发生和发展具有重要意义。

[Objective] To investigate homocysteine （HCY） value on the cardiovascular disease （CVD） and the cerebrovascular disease （CVD） without traditional risk factor. [ Methods ] The plasma HCY levels of 40 patients with CVD without traditional risk factor and 40 normal controls were measured by fluorescent technique. [ Results ] Plasma level of HCY in patients with CVD was obviously higher than that of normal controls （P 〈0.01）. [Conclusions] Hyperhomocysteinemia is an independent risk factor for CVD. HCY is directly related to the formation and development of CVD.