白山市甲型H1N1流感病毒感染状况调查

Influenza A(H1N1) Virus Infection Status in Baishan City

目的掌握白山市不同时期甲型H1N1流感病毒感染水平;了解本市甲型H1N1流感病毒感染的动态变化趋势。方法按照卫生部2009年相关要求,分别于2010年1、3月在白山市抽取5个县(市、区)的人口开展横断面调查。采用多阶段分层随机抽样法,两次横断面共调查1 000人。采用Epidata 3.1软件建立调查数据库,利用SPSS 17.0软件进行分析;采集血清由中国疾病预防控制中心病毒病所统一使用血凝抑制(HI)方法对标本进行检测。结果随时间推移白山市甲型H1N1流感抗体水平阳性率有所下降。5个年龄组抗体水平差异有统计学意义(χ2第1次调查=60.501,P<0.001;χ2第2次调查=14.299,P<0.005)。6～15和16～24岁年龄组人群抗体水平阳性率明显高于平均水平,老年人抗体水平较低,学生抗体阳性率高于其他人群,有疫苗接种史人群抗体水平明显高于无疫苗接种史人群(χ2第1次调查=93.698,P<0.001;χ2第2次调查=63.803,P<0.001)。结论本市人群免疫屏障尚未建立。应进一步加强疫情监测,加强疫苗接种,尤其是老年人的预防接种工作。

Objective To master influenza A（H1N1） at different period level in Baishan,understand dynamic change trends of influenza A infection.Methods 2010,respectively,in March 5 counties were selected in January and March 2010 and people were surveyed by a multi-stage stratified random sampling method,and 1000 persons were investigated by twice cross-sectional surveys.Information database was built with Epidata3.1 software and analyzed with SPSS17.0 software.Blood clots inhibit（HI） method was used to collect serum specimens.Results Influenza A antibody positive rate declined with the time passing in Baishan,The difference of antibody levels of five groups was obvious（χ21st survey=60.501,P0.001;χ22nd survey=14.299,P0.005）.Antibody positive rates of 6-15 and 16-24 years old persons were obviously higher than average level,that of old people was lower,but that of students was higher than that of other people.Antibody rate of population having vaccination history was obviously higher than that of population without having vaccination history（χ21st survey=93.698,P0.001;χ22nd survey=63.803,P0.001）.Conclusion Population immune barrier hasn＇t been established in Baishan city yet.Epidemic monitoring and vaccination should be further strengthened,especially the elderly inoculation work.