摘要
目的:探讨不同程度妊娠期肝内胆汁淤积症(ICP)对胎儿及新生儿的影响。方法:回顾性分析上述产妇围生期临床资料,比较正常产妇与不同程度ICP患者肝功能、胎儿宫内窘迫的发生、羊水污染状况、新生儿状况及新生儿并发症等。结果:无论轻度还是重度ICP组患者体内TBI水平均明显高于正常对照组,胎儿窘迫、羊水污染、新生儿窒息、新生儿低体重以及新生儿多种并发症的发生率明显升高,差异有统计学意义(P<0.05),且与ICP患者的轻重程度呈正相关。结论:在妊娠晚期评估ICP患者病情严重程度,对及时治疗和选择安全有效的妊娠方式,减少ICP患者及新生儿不良事件的发生具有明确的临床意义。
Objective: To research the influence of varying grading intrahepatic cholestasis of pregnancy (ICP) on fetus and neonate. Methods: The above puerpera perinatal's clinical data were retrospectively analyzed, and opportunity of pregnancy termination and perinatal outcome were compared between mild ICP and severe ICP. Results: No matter mild or severe ICP group in patients with TBI levels were significantly higher than that of normal control group, difference between the two groups was significant (P0.05). Conclusion: It is suggested to determine the opportunity of pregnancy termination and the modes of delivery according to different clinical grades and treatments of ICP.
出处
《中国当代医药》
2011年第30期11-12,共2页
China Modern Medicine
关键词
妊娠
肝内胆汁淤积症
不同程度
围生儿结局
Pregnancy
Intrahepatic cholestasis
Varying grading
Pefinatal outcome