手术联合米非司酮治疗子宫内膜异位症的系统评价

Systematic evaluation of endometriosis treated by operation combined with mifepristone

目的:探讨手术联合米非司酮治疗子宫内膜异位症的临床疗效。方法:39例手术联合米非司酮治疗的子宫内膜异位症患者作为观察组,单纯手术治疗者39例作为对照组,比较两组临床疗效。结果:治疗3个月后两组治疗效果比较,观察组总有效率为84.6%(33/39),高于对照组的51.3%(20/39),差异有统计学意义(P<0.05)。两组患者随访6个月,观察组中19例不孕症患者中3例成功受孕,对照组18例不孕症患者中2例成功受孕。结论:手术联合米非司酮治疗子宫内膜异位症效果优于单纯手术治疗,药物不良反应可耐受,易恢复,值得临床推广。

Objective： To investigate the clinical effect of the endometriosis treated by operation combined with mifepristone. Methods： 39 patients with endometriosis treated by operation combined with mifepristone were treated as observation group, and 39 patients with endometriosis treated by operation only as control group, then the clinical effect of the two groups were compared. Results： 3 months after the treatment, the total effective rate of the observation group was 84.6% （33/39）, which was higher than the 51.3% （20/39） of the control group, and showed significant differences （P0.05）. During the 6 months＇ follow-up, 3 cases in the 19 infertility patients of the observation group were conception successfully, and 2 cases in the 18 infertility patients of the control group were conception successfully. Conclusion： The clinical effect of the endometriosis treated by operation combined with mifepristone is superior to the operation, adverse drug reactions can be well tolerated, and recover well, it is worth popularizing.