达克宁栓治疗100例霉菌性阴道炎的疗效观察

Observation about the clinical effect of miconazole suppository on 100 patients with colpomycosis

目的:观察达克宁栓辅助治疗霉菌性阴道炎的临床疗效,探讨其临床应用价值。方法:选取200例自愿参加调查的霉菌性阴道炎患者,按随机方式分为两组,两组患者均给予2%～4%苏打水清洗外阴+中药煎剂熏洗外阴部,观察组(n=100)加用达克宁栓1枚(200mg)放置阴道,以7d为1个疗程,治疗1个疗程后观察两组患者的症状体征改善情况以评价治疗效果。结果:观察组临床治愈89例,显效7例,总有效率为96.0%,对照组临床痊愈51例,显效12例,治疗总有效率为63.0%,两组比较差异有统计学意义(P<0.05);观察组(n=96),临床痊愈或显效时间为(10.5±2.5)d,对照组(n=63)临床痊愈或显效的时间为(17.0±2.0)d,两组比较差异有统计学意义(P<0.05)。结论:碳酸氢钠洗液清洗外阴、中药煎剂熏洗,加上阴道放置达克宁栓治疗霉菌性阴道炎疗效显著,可有效缓解临床症状并缩短治疗疗程,具有临床推广价值。

Objective： To observe the therapeutic efficiency of miconazole suppository on colpomycosis. Methods： 200 patients were divided randomly into 2 groups. All of them took sodium bicarbonate solution （2%-4%） to washed vulva and took the decoction Chinese medicine to fumigation vulva. The treatment group （100 cases） placed a miconazole suppository （200 mg） in vagina once daily. Contrast clinical efficacy after 7 days. Results： There were 89 cases clinical cure and 7 cases markedly in the treatment group, and the control group was 51, 12 cases, the effective rate of the treatment group was 96.0% and the control group was 63.0%, the difference of the two groups was statistically significant （P0.05）. The time consuming of the treatment group was （10.5±2.5） d and the control group was （17.0±2.0） d. The total therapeutic efficiency of the treatment group was much better than the control group （P0.05）. Conclusion： Sodium bicarbonate solution （2%-4%） to wash vulva, decoction Chinese medicine to fumigation vulva and placed a miconazole suppository （200 mg） in vagina is efficient in the treatment of colpomycosis.