复发性外阴阴道念珠菌病的诊疗措施

The Diagnosis and Treatment Measures of Recurrent Vulvovaginal Candidiasis

目的：探索伊曲康唑治疗复发性外阴阴道念珠菌病的临床疗效.方法：选择我院2008年1月～2010年1月收治的复发性外阴阴道念珠菌病患者76例,将上述患者随机分为治疗组40例和对照组36例,观察两组之间的疗效.结果：治疗组1周后的总有效率为92.5%（37/40）,对照组的总有效率为88.9%（32/36）,两组之间总有效率比较无统计学意义（P 〉0.05）.但是两组之间3个月（χ2=5.316,P〈0.05）和6个月（χ2=11.740,P〈0.01）复发率比较有统计学意义.结论：伊曲康唑短程冲击治疗联合硝酸咪康唑栓对复发性外阴阴道念珠菌病的治疗和预防复发有一定疗效,值得在临床推广应用.

Objective：To explore the clinical efficacy of treatment 9f recurrent vulvovaginal eandidiasis by ltraeonazole. Methods：To choose 76 eases treated patients with recurrent vulvovaginal candidiasis from January 2008 to January 2010 in our hospital,the patients were randomly divided into treatment group 36 cases and.control group 40 cases,observed curative effect between two groups. Results：The total effective rate was 92.5% （37/40） in the treatment group after 7 days,the total effective rate was 88.9% （32/36） in the control group,and the total effective rate between the two groups was not significant （P〉0.05）.However, the reettrrenee rate was statistically significant in 3 months and 6 months between the two groups （x 2=5.316,P〈0,05; x ^2=1 ] .740,P〈0.0 1）.Conclusion：Tbere is certain curative effect of recurrent vulvovaginal candidiasis in treatment and prevention by the short-term-itraconazole-impaet therapy combined Miconazole.It is worth applying in the clinical expansion.