不孕不育患者沙眼衣原体感染状况分析

The Infection Situation of Chlamydia Trachomatis in Patients with Infertility

目的:研究广东地区不孕不育患者沙眼衣原体(CT)的感染状况。方法:收集937例不孕不育患者(包括原发不孕不育、继发不孕不育和自然流产病例)的生殖道分泌物标本以及879例正常生育者生殖道分泌物标本,并用胶体金免疫沉析法检测CT抗原。结果:不孕不育组CT感染率为14.94%,显著高于对照组(2.62%);不孕不育女性CT感染率为17.62%,显著高于不育男性的CT感染率(10.93%)。女性原发性不孕、继发性不孕及反复自然流产的CT阳性率分别为16.24%、19.12%、16.67%,三组CT阳性率无统计学意义;男性原发性不育组、继发性不育组的CT性率分别为10.06%、11.65%,差异也无统计学意义。结论:CT感染是引起广东地区男性不育,女性不孕及自然流产的重要病因之一。

Objective：To study the prevalence of Chlamy trachomatis（CT） infection in patients with infertility from Guangdong province. Methods： 937 secretion specimens of genital duct were collected from patients with infertility, including prirrtary infertility, secondary infertility and recurrent spontaneous abortion cases： 879 secretion specimens of genital duct fi＇om fertile persons were collected as contral;and using colloidal gold immuno.precipitation to assay CT antigens in specimens. Results：The Chlamydia trachomatis infection rates of infertility group was 14.94% and significantly higher than normal fertility group （2.62%）; and the CT infection rate of infertile women（17.62%） was also significantly higher than infertile men（10.93%）. The CT-positive rates of women with primary infertility, secondary infertility and recurrent spontaneous abortion were 16.24%. 19.12% and 16.67%. no statistical significance distinguish in the three groups ; The CT-positive rates of male patients with primary infertility and secondary infertility were 10.06%, 11.65%, there is no statistical significance distinguish between the two groups.Conelusion：CT infection is an important cause of male infertility, female infertility, and spontaneous abortion in Guangdong province.