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2型糖尿病患者兄弟姐妹发病顺序调查

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摘要 目的探讨2型糖尿病(T2DM)患者在家族兄弟姐妹间发病的顺序。方法随机问卷调查T2DM患者120例,其中男、女各60例,调查内容包括年龄、发现糖尿病时的年龄、空腹血糖值、兄弟姐妹人数、在兄弟姐妹之间的排序。结果对T2DM患者而言,男女性别之间发病有统计学意义;排行顺序第1、第2与第3、4、5之间比较结果有统计学意义。结论遗传因素在T2DM的发生和发展中起着重要作用,同时其发病还受到环境因素的影响。加强糖尿病教育,同时对该类人群加强DM并发症的筛查,提高其生活质量。
出处 《中国误诊学杂志》 CAS 2011年第30期7435-7436,共2页 Chinese Journal of Misdiagnostics
关键词 糖尿病 2型
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  • 1曾庆萃,田浩明.转录因子7类似物2(TCF7L2)与2型糖尿病发病关系的研究进展[J].华西医学,2007,22(3):693-694. 被引量:1
  • 2Liu Y,Niu NF,Zhu XL,et al.Genetic variation and association analyses of the nuclear factor 1 (nRF1) gene in Chinese patients with type 2 diabetes.Diabetes,2008,57:777-782.
  • 3Nabila BN,Ame′lie B,Christine CP,et al.A variant near MTNR1B is associated with increasedfasting plasma glucose levels and type 2 diabetes risk.Nat Genet,2009,41:89-94.
  • 4Pivovarova O,Nikiforova VJ,Pfeiffer AF,et al.The influence of genetic variations in HHEX gene on insulin metabolism in the Germa MESYBEPO cohort.Diabetes Metab Res Rev,2009,25:156-162.
  • 5Wu Y,Li H,Loos RJ,et al.Common variants in CDKAL1,CDKN2A/B,IGF2BP2,SLC30A8,and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.Diabetes,2008,57:2834-2842.
  • 6Lee YH,Kang ES,Kim SH,et al.Association between polymorphisms in SLC30A8,HHEX,CDKN2A/B,IGF2BP2,FTO,WFS1,CDKAL1,KCNQ1 and type 2 diabetes in the Korean population.J Hum Genet,2008,53:991-998.
  • 7Pascoe L,Tura A,Patel SK,et al.Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function.Diabetes,2007,56:3101-3104.
  • 8Haupt A,Staiger H,Schfer SA,et al.The risk allele load accelerates the age-dependent decline in beta cell function.Diabetologia,2009,52:457-462.
  • 9Omori S,Tanaka Y,Takahashi A,et al.Association of CDKAL1,IGF2BP2,CDKN2A/B,HHEX,SLC30A8,and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population.Diabetes,2008,57:791-795.
  • 10Li X,Allayee H,Xiang AH,et al.Variation in IGF2BP2 interacts with adiposity to alter insulin sensitivity in Mexican Americans.Obesity,2009,15:345-347.

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