肝癌动脉化疗栓塞术预防使用抗菌药物的回顾性分析

Retrospective Analysis of the Antibacterial Use in Transcatheter Arterial Chemoemboliztion for Hepatocellular

目的：分析肝癌动脉化疗栓塞术预防使用抗菌药物情况，为合理使用抗茵药物提供参考。方法：对肝癌动脉化疗栓塞术226例预防使用抗菌药物情况进行了回顾性研究。结果：肝癌动脉化疗栓塞术预防感染抗菌药物使用率为925％：预防使用抗菌药物的主要种类为酶抑制剂复方制剂（464％）、头孢菌素类（184％）、喹诺酮类（152％）；预防使用抗茵药物平均疗程为3d；术后继发感染3例．发生率为13％。结论：癌动脉化疗栓塞术后继发感染比例低，预防使用抗菌药物比例高，不应常规预防用抗菌药物；预防用药的疗程过长。

Objective： To investigate the rationality of antibacterial prophylaxis in transcatheter arterial chemoembolization（TACE）. Methods： 226 transcatheter arterial chemoembolization cases are retrospectively investigated. Results： The rate of antibacterial usage is 92.5%; the most frequently used antibiotics are I^-lactamase inhibitor compound preparation（46.4%）, cephalosporins （18.4%）, quinolones （15.2%）. The average duration of treatment is 3 day. The rate of postoperative infection is 1.3%. Conclusion： The rate of postoperative infection is low, and there is a high rate of antibacterial prophylaxis. Therefore, antibacterial prophylaxis should not be a routine procedure. Moreover, the duration of some treatment is inappropriate.