青岛市4434例正常人群骨密度测定分析

The analysis of bone mineral density results in 4434 healthy people in Qingdao

目的了解青岛市部分正常人群骨密度(BMD)变化的规律,为本地的骨质疏松症(OP)的诊断、预防、治疗提供科学依据。方法应用双能X线骨密度仪,测定青岛市20～79岁健康体检人群中4434人的腰椎(L2-4)、股骨上端(Neck、Ward、Troch)的骨密度,按年龄段分组,5岁为1年龄组,将其分为12组。计算骨量丢失率及患病率,用SPSS13.0软件进行统计学处理,比较各年龄组之间的差异。结果青岛市男女性骨峰值均见于25～29岁年龄组,以后随着年龄增长,骨密度逐渐降低。女性45岁、男性65岁以后骨密度值下降明显,骨量丢失率增加。结论 40岁以后应检测骨密度的变化,监测部位以股骨上端Ward最敏感;OP的防治重点在女性,尤其是绝经期妇女。老年男性,尤其是60岁以上的男性,也不容忽视。

Objective To understand the role of bone mineral density （BMD） alteration in partial healthy people in Qingdao, and to provide scientific evidence for the diagnosis, prevention, and treatment of osteoporosis. Methods BMD of the lumbar vertebra 2-4 （L2-4） and the proximal femur in 20-79 years old healthy people in Qingdao was measured using a dual energy X-ray absorptiometry. They were divided into 12 groups according to every 5-year of age. Bone loss and prevalence were calculated using SPSS 13.0 software. The difference among the groups was compared. Results The peak bone mass appeared in 25-29 years old group both in the male and female residence of Qingdao. BMD decreased along with aging. BMD decreased and bone loss increased obviously in females after 45 years old and in males after 65 years old. Conclusion BMD should be detected in people after 40s. The most sensitive monitor location is Ward＇s region of the proximal femur. The prevention of osteoporosis should be focused on women, especially on postmenopausal women and elderly men over 60s.