大前庭导水管综合征5例临床分析

Clinical analysis of 5 patients with large vestibular aquetube syndrome

目的探讨大前庭导水管综合征的临床特点。方法回顾性分析5例大前庭导水管综合征患者的临床资料。结果本组患者均在儿童或青少年期发病,临床上以反复发作性眩晕和单侧或双侧进行性耳聋为主要表现,病灶侧半规管壶腹嵴功能检查有不同程度的减退,颞骨CT或/和MR I超薄扫描均示患侧前庭导水管扩大。本组5例患者均未行手术治疗,随访1年后发现眩晕发作均有减轻,而听力却继续下降。结论大前庭导水管综合征患者多表现为反复发作性眩晕和单侧或双侧进行性耳聋,颞骨CT和MRI超薄扫描可确诊。大前庭导水管综合征致残率较高,尽早治疗和必要时手术治疗或可有较好疗效。

Objective To investigate the clinical features of large vestibular aquetube syndrome.Methods The clinical data of 5 patients with large vestibular aquetube syndrome were analyzed retrospectively.Results The patients in this group were all onset at childhood or adolescents.The main clinical manifestations were repeated paroxysmal vertigo and unilateral or bilateral progressive deafness.The function of semicircular canal and crista ampullaris at side of lesions.The CT or/and MRI of temporal bone indicated dilated vestibular aquetube at injury side.No one of the 5 patients in this group was treated by operation,and their vertigo turned to be lighter at 1 year later,while their hearing kept reducing.Conclusions The clinical manifestations of large vestibular aquetube syndrome are repeated paroxysmal vertigo and unilateral or bilateral progressive deafness.The CT or/and MRI of temporal bone can make a definite diagnosis.The rate of deformity of large vestibular aquetube syndrome is high,early treatment and necessary operation may be effective.