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听觉诱发电位指数调控丙泊酚靶控输注在无痛结肠镜检查中的应用

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摘要 目的:探讨听觉诱发电位指数用于调控丙泊酚靶控输注麻醉行肠镜检查的可行性。方法:90例患者随机分为无痛肠镜组(A组,n=60)和常规肠镜检查组(B组,n=30),A组又随机分为AAI组(n=30)和对照组(n=30),AAI组是在听觉诱发电位指数指导下调节丙泊酚靶控浓度(Ce),对照组设置初始Ce为2.0μg/mL,以0.2~0.4μg/mL每2min递增,维持于2.5~4.0μg/mL,B组不使用麻醉剂。结果:B组在进镜过程中平均动脉压较进镜前升高(P<0.05),对照组诱导成功后平均动脉压较诱导前下降(P<0.05);与对照组比较,AAI组丙泊酚用量减少,体动次数减少,苏醒时间缩短(P<0.05);AAI组苏醒即刻及5min改良警觉/镇静评分优于对照组(P<0.05)。结论:无痛肠镜是一种安全有效的肠镜检查方法,听觉诱发电位指数可指导丙泊酚靶控输注,用于结肠镜检查可提供满意的麻醉深度,减少麻醉药用量,减少麻醉不良反应及术中体动,缩短苏醒时间,提高苏醒质量。
出处 《中国中西医结合外科杂志》 CAS 2011年第5期521-523,共3页 Chinese Journal of Surgery of Integrated Traditional and Western Medicine
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参考文献6

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