经皮射频消融术治疗脊柱转移肿瘤引起的疼痛

Percutaneous Radiofrequency Ablation for Painful Metastatic Spinal Tumors

目的观察经皮射频消融术治疗脊柱转移肿瘤疼痛的疗效。方法 2006年2月至2010年2月对82例脊柱转移瘤患者123个椎体应用经皮穿刺射频消融术治疗。随访6～18个月,平均13.6个月。对患者术前、术后3d、1周、3个月、6个月、12个月时的疼痛缓解程度应用视觉模拟评分法(visual analog scale,VAS)进行评分及评估分级。结果 VAS评分术前为(8.09±1.18)分,术后3d为(1.80±0.60)分,较术前明显降低,有统计学意义(P<0.05);术后各时间点疼痛缓解优良率均大于80%。术后82例患者123个病变椎体病理结果证实为骨转移瘤,术中、术后无严重并发症。结论经皮穿刺射频消融术具有创伤小、操作简单、并发症少等优点,能够有效缓解脊柱转移瘤患者疼痛,改善患者生活质量。

Objective To evaluate the clinical effect of percutaneous radiofrequency ablation（RFA） for painful metastatic spinal tumors.Methods From February 2006 to February 2010,82 patients with 123 diseased regions,with the diagnosis of metastatic spinal tumors were included in the study.The follow-up is 6～18 months,with an average of 13.6 months.The clinical outcome was self-measured by VAS scale at 3 days,1 week,3 months,6 months and 12 months respectively.Results The postoperative VAS scorereduced significantly.Pain relief beyond 80% was reached at any time point.No major complications occurred.Biopsy outcomes were positive in all patients.Conclusion The percutaneous radiofrequency-ablation is simple minimally invasive treatment with few complications,which can release pain,and improve life of patients with metastatic spinal tumors.