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不同浓度舒芬太尼混合罗哌卡因行硬膜外镇痛的临床观察 被引量:3

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摘要 目的比较不同浓度舒芬太尼混合罗哌卡因用于术后持续硬膜外镇痛的镇痛效果及相关不良反应。方法 36例择期手术的妇科、泌尿科患者随机均分成3组,术后硬膜外镇痛分别使用舒芬太尼浓度0.75μg/ml(A组)、1.0μg/ml(B组)、1.25μg/ml(C组)混合0.2%罗哌卡因。镇痛泵固定持续输注速度2ml/h,于术后不同时点随访,评估静止、活动时切口的疼痛程度、下肢运动阻滞程度、镇静深度及相关不良反应。结果 3组患者皆获得较为满意的镇痛效果,未发现低血压及呼吸抑制,各组患者术后各时点静止、活动时VAS评分、警觉/镇静评分、改良Bromage评分、不良反应的比较,差异无统计学意义(P>0.05)。结论 0.75μg/ml舒芬太尼混合0.2%罗哌卡因用于低输注速度术后持续硬膜外镇痛效果明确,进一步增加舒芬太尼浓度,镇痛效果未见明显提高。
出处 《福建医药杂志》 CAS 2011年第5期116-118,共3页 Fujian Medical Journal
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