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瑞芬太尼全麻对胃癌手术患者血流动力学、血糖、皮质醇及儿茶酚胺的影响 被引量:11

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摘要 目的观察瑞芬太尼全麻对胃癌手术患者的血流动力学、血糖(Glu)、皮质醇(Cor)及儿茶酚胺的影响。方法择期行胃癌根治术患者60例,随机平均分为2组,R组30~60 s内静脉注射瑞芬太尼1μg/kg,术中持续泵注瑞芬太尼0.05~0.1μg/(kg.min),F组诱导期静注芬太尼4μg/kg,术中芬太尼根据BIS深度情况给予0.05~0.1 mg/次。记录麻醉中的平均动脉压(MBP)、心率(HR)变化情况,并同时测Glu、Cor、肾上腺素(E)及去甲肾上腺素浓度。记录自主呼吸恢复时间、清醒时间、拔管时间及拔管时躁动例数。结果麻醉诱导后,R组MBP、HR、Glu、Cor、E指标、插管时呛咳反应例数及拔管时躁动例数低于F组(P<0.05)。结论瑞芬太尼能明显减轻麻醉和手术对患者引起的应激反应,效果优于芬太尼。
作者 王昊
出处 《山东医药》 CAS 北大核心 2011年第40期107-108,共2页 Shandong Medical Journal
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同被引文献88

  • 1马浩南,赵军.瑞芬太尼药理学和临床应用进展[J].河北医药,2006,28(2):132-134. 被引量:25
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