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血管内皮生长因子和微血管密度在非小细胞肺癌组织中的表达和意义 被引量:4

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摘要 目的探讨血管内皮生长因子(VEGF)和微血管密度(MVD)在非小细胞肺癌(NSCLC)组织中的表达和意义。方法回顾性分析62例NSCLC患者的临床资料,采用免疫组织化学SP法检测标本中的VEGF和MVD,并与同期化检的60例患者作对照。结果 NSCLC组的VEGF阳性表达率和MVD计数均明显高于对照组,差异有统计学意义(P<0.05)。VEGF阳性表达和MVD与TNM分期、分化程度及有无转移等有关(P<0.05),与病理类型、年龄、性别无关(P>0.05)。结论 VEGF和MVD在NSCLC患者组织中呈过度表达,并与肿瘤的发生、发展、侵袭等密切相关。
出处 《河北医药》 CAS 2011年第21期3246-3247,共2页 Hebei Medical Journal
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