慢性心力衰竭患者心率震荡现象的变化及其意义

Change and significance of heart rate turbulence in patients with chronic heart failure

目的探讨慢性心力衰竭(CHF)患者心率震荡(HRT)现象的特征,及其与左室射血分数(LVEF),心率变异性(HRV)等的相关性。方法选择心衰患者58名(心衰组)和非心衰患者65名(对照组),从动态心电图和超声心动图获得HRT、HRV、左室舒张末期内径(LVEDD)、LVEF等指标,并对这些指标进行分析。结果心衰组和对照组的HRT、HRV、LVEF、LVEDD、QT间期离散度(QTcd)、平均心率有显著统计学差异,而24 h室性期前收缩的数量没有统计学意义。HRT与LVEF、LVEDD、SDNN等指标呈相关关系。结论心衰组患者HRT减弱,HRT可以反映心脏自主神经功能的状态。

Objective To analyze the feature of heart rate turbulence（HRT） in patients with chronic heart failure（CHF） and the relation between HRT,left ventricular ejection fraction（LVEF）,heart rate variability（HRV） and so on. Methods 58 patients with chronic heart failure（CHF group） and 65 cases of non-chronic heart failure（control group） were chosen,these indexes were recorded including HRT,HRV,LVEF,LVEDD and so on from echocardiography and 24-hour Holter monitoring.Statistical method was used to analyze all the data. Results There was statistical difference in HRT,HRV,LVEF,LVEDD,QTcd and mean heart rate,while there was no statistical difference in ventricular premature complexes of 24 hours between CHF patients and control group.HRT were correlated with LVEF,LVEDD and SDNN. Conclusion The HRT in patients with CHF was decreased.HRT could reflect cardiac autonomic nerve status.