期刊文献+

小胶质细胞在糖尿病视网膜病变发病机制中的作用 被引量:1

Role of Microglia in the Pathology of Diabetic Retinopathy
下载PDF
导出
摘要 本文阐述近年来通过科学研究,科学工作者坚持科学精神,努力探索小胶质细胞在糖尿病视网膜病变发病机制中所起的作用,提出其可能通过炎症因子的刺激,释放炎症介质,参与免疫炎症反应,从而损伤视网膜血管。了解其作用机制,为糖尿病视网膜病变的防治提供了新的思路。 This article mainly discussed the scientists insisting on scientific research work and trying hard to discover the role of microglia in the pathology of diabetic retinopathy. Retinal microglia was stimulated by inflammatory factors, released cytokines and mediated inflammatory processes,which often damage the retinal vessels. It indicates that knowing the function of retinal microglia will get new ideas to the prevention and treatment of diabetic retinopathy.
出处 《医学与哲学(B)》 2011年第10期54-55,共2页 Medicine & Philosophy(B)
关键词 视网膜小胶质细胞 糖尿病视网膜病变 retinal microglia cell, diabetic retinopathy
  • 相关文献

参考文献15

  • 1Heckenlively J R. Retina and vitreous (Basic and Clinical Science Course 1994-1995,Section 12)[M],AAO,1994,51.
  • 2黄国琼,秦宇彤,罗长坤.生命科学的发展对医学的影响[J].医学与哲学(A),2011,32(2):13-15. 被引量:12
  • 3李红涛,张金钟,邱明才.医学发展中的整体观念与学科综合[J].医学与哲学(A),2009,30(4):8-9. 被引量:15
  • 4王爱玲,吴玲玲.视网膜小胶质细胞与眼科疾病[J].国外医学(眼科学分册),2004,28(6):418-421. 被引量:6
  • 5Navascues J, Moujahid A, Almendros A, et al. Origin of microglia in the quail retina:central to peripheral and vitreal to scleral migration of microglial precursors during development[J]. J Comp Neurol, 1995,354:209-228.
  • 6Kreutzberg G W. Microglia:a sensor for pathological events in the CNS[J]. Trends Neurosci, 1996,19 : 312- 318.
  • 7Bodeutsch N, Thanos S. Migration of phagocytotic cells and devel- opment of the murine intraretinal microglial network: an in vivo study using fluorescent dyes[J]. Glia, 2000,32 : 91 - 101.
  • 8Wierzba-Bobrowicz T,Schmidt- Sidor B, Gwiazda E, et al. Major histocompatibility complex class Ⅱ expression in the frontal and temporal lobes in the human fetus during development[J]. Folia Neuropathol, 2000,38: 73- 77.
  • 9Provis J M, Diaz C M, Penfold P L. Microglia in human retina: a heterogeneous population with distinct ontogenies[J]. Perspect Dev Neurobiol, 1996,3 : 213 - 222.
  • 10Feit- Leichman R A, Kinouchi R, Takeda M, et al. Vascular dam- age in a mouse model of diabetic retinopathy: relation to neuronal and glial changes [J]. Invest Ophthalmol Vis Sci, 2005,46 ( 11 ) : 4281 -4287.

二级参考文献41

  • 1邱明才.器官医学与内科的综合优势[J].中华内科杂志,2004,43(7):483-484. 被引量:13
  • 2戴尅戎.微创外科理念的形成与发展[J].中华创伤杂志,2005,21(1):18-20. 被引量:34
  • 3高桦,邱明才.应加强对部分2型糖尿病患者多器官免疫损伤的研究[J].中华医学杂志,2005,85(12):793-795. 被引量:46
  • 4朱梅,邱明才.骨质量与肾小管疾病[J].中华医学杂志,2005,85(37):2593-2594. 被引量:6
  • 5Gale EA,陈洁莉,邱明才.淡化糖尿病的分型[J].国际内分泌代谢杂志,2006,26(6):371-374. 被引量:19
  • 6Building a hand held lab on-a-chip Io simplify blood tests[EB/OL]. [2006- 08- 28]. http ://www. nsbri, org/.
  • 7Kobayashi S, Boggon T J, Dayaram T, et al. EGFR mutation and re sisiance of non-small-cell lung cancer to gefitinib[J]. The New England Journal of Medicine Med, 2005,352 (8) 786 - 792.
  • 8Mok T S, Wu Y L, Thongprasert S, et al. Gefitinib or Carboplatin- Paclitaxel in Pulmonary Adenocarcinoma[J]. The New England Journal of Medicine Med,2009,361 (10):947-957.
  • 9Karapetia C S,Khambata-Ford S,Jonker DJ,et al. K-rasmuta tions and benefit from cetuximab in advanced colorectal cancer[J].The New England Journal of Medicine Med,2008,359(17) :1757- 1765.
  • 10Turke A B, Zejnullahu K, Wu Y L, et al. Preexistenee and clonal selection of MET amplification in EGFR mutant NSCLC[J]. Cancer Cell,2010,17(1) :77-88.

共引文献30

同被引文献21

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部