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5-溴-2-甲氧基苯酚的合成

Synthesis of 5-Bromo-2-Methoxyphenol
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摘要 5-溴-2-甲氧基苯酚是一种重要的农药、医药中间体,本文以邻甲氧基苯酚为原料,乙酰化、溴化、脱保护得到5-溴-2-甲氧基苯酚,总收率为64.3%,产物的结构通过1HNMR、13CNMR及元素分析进行验证。 5-bromo-2-methoxyphenol was synthesized from guaiacol via protection of phenolic hydroxyl group, bromination with bromine, and deprotection, with the overall yield of 64.3%. The structure of the product was confirmed by 1HNMR, 13CNMR and elementary analysis.
作者 陈正许 蒋成君
机构地区 浙江新东港药业股份有限公司 浙江科技学院生物与化学工程学院
出处 《浙江化工》 CAS 2011年第10期6-8,共3页 Zhejiang Chemical Industry
基金 浙江省重点科技创新团队项目(2011R09028-10)
关键词 邻甲氧基苯酚 溴化 5-溴-2-甲氧基苯酚 脱保护 guaiacol bromination 5-bromo-2-methoxyphenol deprotection
分类号 TQ243.12 [化学工程—有机化工]
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参考文献9

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二级参考文献28

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共引文献2

浙江化工
2011年 第10期

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