白芍炮制品中芍药苷水提取释放速度的初步研究

Preliminary Study on Release Rate of Paeoniflorin in Paeonia lactiflora Processed Products by Water Extraction

目的:考察不同炮制品在煎煮过程当中对芍药苷浸出的释放规律。方法:单独煎煮芍药炮制品饮片。HPLC测定煎煮液与饮片中芍药苷含量。结果:白芍经炮制后其芍药苷含量均下降,焦白芍和白芍炭下降最多。30 min内,焦白芍释放最快,芍药苷煎出量,以生白芍与焦白芍为高。结论:各种炙法炮制芍药,均会造成芍药苷含量下降,以白芍炭和焦白芍下降最显著;炮制对煎煮过程中芍药苷的释放有明显促进作用,焦白芍释放速度最快。

Objective：To investigate release discipline of paeoniflorin in different processed Paeonia lactiflora in boiling process.Method： P.lactiflora processed products were boiled alone.HPLC was used to determine the content of paeoniflorin in boiling liquid and decoction pieces.Result： The content of paeoniflorin in P.lactiflora decreased after processed.P.lactiflora carbon and baked P.lactiflora decreased the lowest,release speed in baked P.lactiflora was the highest during 30 min.The content of paeoniflorin in P.lactiflora and baked P.lactiflora was the highest after boiled.Conclusion： Processing made paeoniflorin declined in all processed products,declined most significant were P.lactiflora and baked P.lactiflora;but it could increase release speed,especial in baked P.lactiflora.