黎药角花胡颓子乙酸乙酯萃取部位的化学成分

Research on Chemical Constituents of Ethyl Acetate Fraction from Li Nationality Medicine Elaeagnus gonyanthes Caulis et Folium

目的:研究黎药角花胡颓子茎叶乙酸乙酯萃取部位的化学成分。方法:黎药角花胡颓子茎叶用70%乙醇提取后,依次用石油醚、乙酸乙酯、正丁醇萃取,对乙酸乙酯萃取部位采用各种柱色谱方法进行分离、纯化,通过理化性质、薄层色谱及波谱分析等方法对分离得到的化合物进行结构鉴定。结果:从角花胡颓子茎叶乙酸乙酯萃取部位分离得到6个化合物,分别鉴定为β-谷甾醇(1),羽扇豆醇(2),齐墩果酸(3),熊果酸(4),α-香树脂(5),β-胡萝卜苷(6)。结论:化合物1～6均为首次从该植物中分离得到。

Objective：To study the chemical constituents of ethyl acetate fraction from Elaeagnus gonyanthes Caulis et Folium.Method： The medicinal plants were first extracted by 70% ethanol-water and then partitioned with petroleum ether,ethyl acetate and n-butanol,respectively.The chemical constituents of the ethyl acetate fraction were separated and purified by column chromatography methods and their structures were identified by physiochemical properties,thin-layer chromatography and spectra analyses.Result： 6 compounds were isolated and identified as β-sitosterol（1）,lupeol（2）,oleanolic acid（3）,ursolic acid（4）,α-amyrin（5）,β-daucosterol（6）,respectively.Conclusion： All the six compounds were isolated from this plant for the first time.